Tag: 200-300

Rh-Catalyzed Dehydrogenative Cyclization Leading to Benzosilolothiophene Derivatives via Si-H/C-H Bond Cleavage was written by Mitsudo, Koichi;Tanaka, Seiichi;Isobuchi, Ryota;Inada, Tomohiro;Mandai, Hiroki;Korenaga, Toshinobu;Wakamiya, Atsushi;Murata, Yasujiro;Suga, Seiji. And the article was included in Organic Letters in 2017.Computed Properties of C8H4Br2S This article mentions the following:

Straightforward syntheses leading to π-extended benzosilolothiophene (BST) derivatives by Rh-catalyzed dehydrogenative cyclization reactions were developed. Electron-deficient ligands were effective for the reactions, and dppe-F₂₀ gave the best result. This method could be applied to the synthesis of highly π-extended ladder-type BST derivatives, which exhibited fluorescence. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Computed Properties of C8H4Br2S).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is also used in the manufacturing of dyes such as thioindigo.Computed Properties of C8H4Br2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Sonogashira reaction of 5-substituted 3-(prop-2-yn-1-yl)oxolan-2-ones was written by Ghochikyan, T. V.;Samvelyan, M. A.;Galstyan, A. S.;Gevorgyan, A.;Vardanyan, G.;Grigoryan, T.;Langer, P.. And the article was included in Russian Journal of Organic Chemistry in 2017.Formula: C8H4Br2S This article mentions the following:

Palladium-catalyzed cross-coupling of 5-methyl- and 5,5-dimethyl-3-(prop-2-yn-1-yl)oxolan-2-ones with dihaloarenes (dihaloheteroarenes) gave mixtures of the corresponding mono-coupling products I (R = H, Me; R¹ = 2-BrC₆H₄, 4-Br-2-F₃CC₆H₃, 4-bromothiophen-3-yl, etc.) and bis-coupling products II (X = 1,3-C₆H₄, 2-CF₃-1,4-C₆H₃, thiophene-3,5-diyl, etc.). The latter can be obtained as the major products by variation of the catalytic system. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Formula: C8H4Br2S).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Formula: C8H4Br2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Room-Temperature Hydrodehalogenation of Halogenated Heteropentalenes with One or Two Heteroatoms was written by Chelucci, Giorgio;Baldino, Salvatore;Ruiu, Andrea. And the article was included in Journal of Organic Chemistry in 2012.Recommanded Product: 2,3-Dibromobenzo[b]thiophene This article mentions the following:

The pair NaBH₄-TMEDA as a hydride source and catalytic PdCl₂(dppf) in THF prove to be an efficient system for the hydrodehalogenation of bromo(chloro)-heteropentalenes with one or two heteroatoms, while Pd(OAc)₂/PPh₃ is able to reduce reactive haloheteropentalenes, and PdCl₂(tbpf) allows the removal of the 2-chlorine from a thiophene ring. The reaction conditions tolerate various functional groups, allowing highly chemoselective reactions in the presence of halide, ester, alkyne, alkene, and nitrile substituents and also showing good efficiency in the regioselective hydrodehalogenation of a variety of polyhalogenated substrates. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Recommanded Product: 2,3-Dibromobenzo[b]thiophene).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Recommanded Product: 2,3-Dibromobenzo[b]thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis and application of 1-(2-methyl-3-benzothienyl)-2-[3-methyl-2-thienyl]perfluorocyclopentene was written by Li, Gang;Liu, Gang;Pu, Shouzhi. And the article was included in Advanced Materials Research (Durnten-Zurich, Switzerland) in 2015.HPLC of Formula: 10243-15-9 This article mentions the following:

A novel unsym. photochromic diarylethene compound 1-(2-methyl-3-benzothienyl)-2-[3-methyl-2-thienyl]perfluorocyclopentene (I) was designed and constructed successfully. Its optoelectronic properties have been discussed systematically, such as photochromic, fluorescence switch, kinetics experiments in hexane solution and PMMA. The consequences showed that this compound exhibited good reversible photochromism. The maxima absorption of compound closed-ring isomer is 468 nm. Upon irradiation with 297 nm UV light, its fluorescence intensity decreased along with the photochromism from open-ring isomers to closed-ring isomers upon irradiation with 297 nm UV light. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9HPLC of Formula: 10243-15-9).

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is also used in the manufacturing of dyes such as thioindigo.HPLC of Formula: 10243-15-9

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Thermally-stable 2,3-diphenylated benzotiophene containing host materials for red phosphorescent organic light-emitting diodes was written by Jeon, Joon Ho;Lee, Nam-Jin;Lee, Ji-Hoon;Suh, Min Chul. And the article was included in Dyes and Pigments in 2014.Related Products of 6287-82-7 This article mentions the following:

This study reports a series of benzo[b]thiophene (BT) derivatives with good electronic properties as host materials for red phosphorescent organic light-emitting diodes (PHOLEDs). We applied thermally-stable materials for red PHOLEDs which contain BT and carbazole moieties which also provide a good charge transport ability, as well as a good charge confinement effect (T₁ > 2.25 eV). To control the appropriate charge transporting ability, two different structures having one or two carbazole units connected to the single BT moiety were prepared Using this approach, we found that the material with a single carbazole and a single BT unit showed the best current efficiency and external quantum efficiency (up to 23.6 cd/A and 12.8%, resp.). The results of the experiment also suggest that BT could be used as an electron-transporting unit when utilized with carbazole moiety, although it has previously been utilized as a p-type material. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Related Products of 6287-82-7).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Related Products of 6287-82-7

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Reaction of halothianaphthenes with metal amides was written by Reinecke, Manfred G.;Hollingworth, T. A.. And the article was included in Journal of Organic Chemistry in 1972.SDS of cas: 6287-82-7 This article mentions the following:

2-Halothianaphthenes react with metal amides in liquid NH3 to give the 3-isomers which are stable under the reaction conditions. No amines or polyhalo compounds were detected. 2,3-Dibromothianaphthene is converted to 3-bromothianaphthene either with or without added thianaphthene. The former instance suggests an intermol. transhalogenation involving carbanions and the latter a dehalogenation via BrNH2. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7SDS of cas: 6287-82-7).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is also used in the manufacturing of dyes such as thioindigo.SDS of cas: 6287-82-7

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Efficient synthesis of chiral 2,3-dihydro-benzo[b]thiophene 1,1-dioxides via Rh-catalyzed hydrogenation was written by Liu, Gongyi;Zhang, Heng;Huang, Yi;Han, Zhengyu;Liu, Gang;Liu, Yuanhua;Dong, Xiu-Qin;Zhang, Xumu. And the article was included in Chemical Science in 2019.Reference of 6287-82-7 This article mentions the following:

Rh-catalyzed asym. hydrogenation of prochiral substituted benzo[b]thiophene 1,1-dioxides was successfully developed, affording various chiral 2,3-dihydrobenzo[b]thiophene 1,1-dioxides I (R = H, 6-MeO; R¹ = C₆H₅, 4-MeOC₆H₄, 4-FC₆H₄, etc.; R² = C₆H₅, 4-MeOC₆H₄, 3-H₃CC₆H₄, etc.) with high yields and excellent enantioselectivities (up to 99% yield and >99% ee). In particular, for challenging substrates, such as aryl substituted substrates with sterically hindered groups and alkyl substituted substrates, the reaction proceeded smoothly in catalytic system with excellent results. The gram-scale asym. hydrogenation proceeded well with 99% yield and 99% ee in the presence of 0.02 mol% (S/C = 5000) catalyst loading. The possible hydrogen-bonding interaction between the substrate and the ligand may play an important role in achieving high reactivity and excellent enantioselectivity. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Reference of 6287-82-7).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Reference of 6287-82-7

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis of 2,3-Disubstituted Benzo[b]thiophenes via Palladium-Catalyzed Coupling and Electrophilic Cyclization of Terminal Acetylenes was written by Yue, Dawei;Larock, Richard C.. And the article was included in Journal of Organic Chemistry in 2002.Name: 2,3-Dibromobenzo[b]thiophene This article mentions the following:

2,3-Disubstituted benzo[b]thiophenes, e.g., I, have been prepared in excellent yields via coupling of terminal acetylenes with com. available o-iodothioanisole in the presence of a palladium catalyst and subsequent electrophilic cyclization of the resulting o-(1-alkynyl)thioanisole derivatives I₂, Br₂, NBS, p-O₂NC₆H₄SCl, and PhSeCl have been utilized as electrophiles. Aryl-, vinyl-, and alkyl-substituted terminal acetylenes undergo this coupling and cyclization to produce excellent yields of benzo[b]thiophenes. (Trimethylsilyl)acetylene also undergoes this coupling/cyclization process with I₂, NBS, and the sulfur and selenium electrophiles to afford the corresponding 2-(trimethylsilyl)benzo[b]thiophenes. However, cyclization of the silyl-containing thioanisole using Br₂ affords 2,3-dibromobenzo[b]thiophene. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Name: 2,3-Dibromobenzo[b]thiophene).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Name: 2,3-Dibromobenzo[b]thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Research on photochromic materials with synthesis and properties of 1-(2-methyl-3-benzothiophene)-2-[2-methyl-5-(3-cyanophenyl)-3-thienyl]perfluorocyclopentene was written by Liao, Guanming;Zheng, Chunhong;Pu, Shouzhi. And the article was included in Applied Mechanics and Materials in 2014.Application of 10243-15-9 This article mentions the following:

An asym. photochromic diarylethene, 1-(2-Methyl-3-benzothiophene)-2-[2-methyl-5-(3-cyanophenyl)-3-thienyl]perfluorocyclopentene (I) was synthesized and its photochromic and fluorescent properties in hexane solution as well as PMMA films were investigated in detail. Exptl. results showed that compound I exhibited remarkable photochromism. Upon irradiation with 297 nm UV light, the colorless solution of compound I turned to violet with a new visible absorption band centered at 535 nm (ε = 1.08 x 10⁴ L mol^-1 cm^-1) attributable to the closed-ring isomer II. The emission intensity of diarylethene I in a photostationary state was quenched to calculated 32% in hexane and 43% in PMMA film. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9Application of 10243-15-9).

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Application of 10243-15-9

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Structurally Diverse π-Extended Conjugated Polycarbo- and Heterocycles through Pd-Catalyzed Autotandem Cascades was written by Barroso, Raquel;Cabal, Maria-Paz;Badia-Laino, Rosana;Valdes, Carlos. And the article was included in Chemistry – A European Journal in 2015.Formula: C8H4Br2S This article mentions the following:

The Pd-catalyzed reaction between 2,2′-dibromobiphenyls and related systems with tosylhydrazones gives rise to new π-extended conjugated polycarbo- and heterocycles through an autotandem process involving a cross-coupling reaction followed by an intramol. Heck cyclization. The reaction shows wide scope regarding both coupling partners. Cyclic and acyclic tosylhydrazones can participate in the process. Addnl., a variety of aromatic and heteroaromatic dibromoderivatives have been employed, leading to an array of diverse scaffolds featuring a fluorene or acridine central nucleus, and containing binaphthyl, thiophene, benzothiophene and indole moieties. The application to appropriate tetrabrominated systems led to greater structural complexity through two consecutive autotandem cascades. The photophys. properties of selected compounds were studied through their absorption and emission spectra. Fluorescence mols. featuring very high quantum yields were identified, showing the potential of this methodol. in the development of mols. with interesting optoelectronic properties. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Formula: C8H4Br2S).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Formula: C8H4Br2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem