1127-35-1, Benzo[b]thiophene-3(2H)-one 1,1-Dioxide is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,1127-35-1
To a solution of 3,4,5-trimethoxybenzaldehyde (1) (0.392 g, 2.00 mmol) in acetic acid (10 mL) piperidine (10% mol equiv) and benzo[b]thiophen-3(2H)one 1,1-dioxide (2) (0.364 g, 2.00 mmol) were added. The reaction mixture was stirred under reflux for 30 min. After cooling the precipitate was filtered off and crystallised from a mixture of acetic acid and methanol giving 3c (0.505 g, 70%) as yellow crystals, Rf=0.58 (50% EtOAc/hexane), mp 203-205 C. 1H NMR (CDCl3) delta: 3.95 (s, 6H), 3.99 (s, 3H), 7.43 (s, 2H), 7.83 (dd, J=7.7, 7.7 Hz, 1H), 7.91 (s, 1H), 7.92 (dd, J=7.7, 7.7 Hz, 1H), 8.03 (d, J=7.7 Hz, 1H), 8.10 (d, J=7.7 Hz, 1H). 13C NMR (CDCl3) delta: 56.4, 61.2, 111.2, 121.4, 124.8, 125.5, 129.5, 132.4, 134.2, 136.5, 143.5, 144.2, 145.4, 153.3, 178.8. IR (film) nu: 1506, 1578, 1702 cm-1. MS (+ESI) m/z (relative intensity) 361 ([M+H]+, 100). Anal. Calcd for C18H16O6S: C 59.99; H 4.48; found: C 59.64; H 4.56.
The synthetic route of 1127-35-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Cekavicus, Brigita; Vigante, Brigita; Rucins, Martins; Birkmane, Kintija; Petrova, Marina; Belyakov, Sergey; Zuka, Liga; Plotniece, Aiva; Pajuste, Karlis; Gosteva, Marina; Sobolev, Arkadij; Tetrahedron; vol. 69; 26; (2013); p. 5550 – 5557;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem