Tag: 112.1927

Substituent Effects on the Thermochemistry of Thiophenes. A Theoretical (G3(MP2)//B3LYP and G3) Study was written by Notario, Rafael;Temprado, Manuel;Roux, Maria Victoria;Liebman, Joel F.. And the article was included in Journal of Physical Chemistry A in 2012.Electric Literature of C6H8S This article mentions the following:

Very good linear correlations between exptl. and calculated enthalpies of formation in the gas phase (G3(MP2)//B3LYP and G3) for 48 thiophene derivatives were obtained. These correlations permit a correction of the calculated enthalpies of formation to estimate more reliable exptl. values for the enthalpies of formation of substituted thiophenes, check the reliability of exptl. measurements, and also predict the enthalpies of formation of new thiophenes that are not available in the literature. Also, the difference between the enthalpies of formation of isomeric thiophenes with the same substituent in positions 2 and 3 of the ring was analyzed. Likewise, a comparison of the substituent effect in the thiophene and benzene rings was established. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Electric Literature of C6H8S).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Electric Literature of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Properties and deep hydrodesulfurization of MIP naphtha was written by Pang, Hong;Zhao, Leping;You, Bailing;Duan, Weiyu;Liu, Jihua. And the article was included in Lianyou Jishu Yu Gongcheng in 2006.Safety of 3-Ethylthiophene This article mentions the following:

The variations of sulfur and olefin in FCC naphtha in typical Chinese refineries are studied and MIP naphtha and conventional FCC naphtha are compared in respect of properties. When the MIP naphtha with 31.0 v% olefin is treated by selective hydrodesulfurization process-OCT-M developed by SINOPEC Fushun Research Institute of Petroleum and Petrochems., the sulfur is reduced to less than 50 ppm from 664 ppm. Octane loss is only 0.7-1.7%. The process provides a flexible and economic solution for the production of cleaner gasoline of Euro IV specifications from MIP naphtha in refineries. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Safety of 3-Ethylthiophene).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Safety of 3-Ethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

DDQ-Catalyzed Direct C(sp³)-H Amination of Alkylheteroarenes: Synthesis of Biheteroarenes under Aerobic and Metal-Free Conditions was written by Song, Chunlan;Dong, Xin;Yi, Hong;Chiang, Chien-Wei;Lei, Aiwen. And the article was included in ACS Catalysis in 2018.Electric Literature of C6H8S This article mentions the following:

A strategy for oxidative Csp³-H/N-H cross-coupling is presented. This reaction successfully utilizes 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) and tert-Bu nitrite (TBN) as co-catalysts to construct the biomedical applicable biheteroarenes under aerobic conditions. Notably, this amination reaction is successful with a wide range of alkylheteroarenes and could be used as a functionalization tactic for pharmaceutical research and other areas. Furthermore, preliminary mechanistic studies indicate that the C-N bond formation proceeds through the nucleophilic attack of azole to the carbon cation. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Electric Literature of C6H8S).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Electric Literature of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem