Tag: 100-200

Electric Literature of C6H6OSIn 2020 ,《A novel bromo-substituted thiophene based centrosymmetric crystals: Thermal, mechanical, and third order NLO properties for the optical limiting applications》 was published in Physica B: Condensed Matter (Amsterdam, Netherlands). The article was written by Haleshappa, D.; Jayarama, A.; Quah, Ching Kheng; Kwong, Huey Chong. The article contains the following contents:

A thiophene based bromo substituted novel chalcone derivative (E)-3-(4-bromophenyl)-1-(thiophen-2yl)prop-2-en-1-one (2AT4B) is synthesized and crystals are grown using solution slow evaporation method at ambient temperature The single crystal XRD anal. is accomplished to confirm the three dimensional structure of the grown crystals and 2AT4B crystallizes with orthorhombic crystal system under centrosym. space group Pbca with the lattice parameters a = 6.0073(6) Å, b = 13.9765(14) Å, c = 28.1(3) Å, a = β = γ = 900 and V = 2359.3(4) Å3. The functional groups and material purity is confirmed by FT-IR, proton NMR, and carbon NMR techniques. The crystal is subjected to mech. and thermal anal. using vicker’s microhardness test, differential scanning calorimetric, and thermogravimetric measurements and is thermally stable up to 134.04°C. The synthesized mol. was characterized by UV-Vis-NIR spectrometer. The photoluminescence spectrum reveals violet light emission property 2AT4B crystal. In the visible region, 2AT4B crystal processes extensive optical transmission. In a continuous wave mode, the third-order NLO parameters are measured with Z-Scan technique. The open aperture data was used to study the optical limiting behavior of chalcone crystal. Nonlinear optical studies show that the 2AT4B crystal is a promising source for applications in photonic and optical power limiting devices. In the experimental materials used by the author, we found 1-Thiophen-2-yl-ethanone(cas: 88-15-3Electric Literature of C6H6OS)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Electric Literature of C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Sasane, Sachin A.; Husain, Mofazzal; Bhise, Nandu B.; Singh, Girij P.; Joseph, Alex; Shenoy, Gautham G. published their research in Organic Preparations and Procedures International in 2021. The article was titled 《An Improved Process for Synthesis of (S)-Duloxetine Hydrochloride Involving Enzymatic Asymmetric Carbonyl Reduction on a Novel Ketoamine》.Product Details of 88-15-3 The article contains the following contents:

A new ketoamine intermediate was synthesized and devised exptl. conditions to obtain 100% ee for the carbonyl reduction during the synthesis of (S)-duloxetine hydrochloride I using com. available ketoreductase enzymes. The experimental part of the paper was very detailed, including the reaction process of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Product Details of 88-15-3)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Product Details of 88-15-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

COA of Formula: C6H6OSIn 2020 ,《Design, molecular docking, synthesis and biological evaluation of novel 2,5-substituted imidazole derivatives as anti-inflammatory agents》 was published in International Journal of Pharma and Bio Sciences. The article was written by Monalika, Akepogu; Bhargavi, M. Vijaya. The article contains the following contents:

In the current study 2,5-disubstituted imidazoles were synthesized starting from 2-acetyl thiophene. All the synthesized imidazoles were subjected to insilico docking studies (PDB ID:1N26) using AUTODOCK vina software. All the synthesized derivatives were evaluated for invitro anti-inflammatory activity. The experimental part of the paper was very detailed, including the reaction process of 1-Thiophen-2-yl-ethanone(cas: 88-15-3COA of Formula: C6H6OS)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. COA of Formula: C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《Base-free oxidation of alcohols enabled by nickel(II)-catalyzed transfer dehydrogenation》 was written by Ye, Danfeng; Liu, Zhiyuan; Sessler, Jonathan L.; Lei, Chuanhu. Quality Control of 1-Thiophen-2-yl-ethanone And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:

An efficient nickel(II)-catalyzed transfer dehydrogenation oxidation of alcs. was reported that relies on cyclohexanone as the formal oxidant and does not require the use of an external base. The synthetic utility of this protocol was demonstrated via the facile oxidation of structurally complicated natural products. After reading the article, we found that the author used 1-Thiophen-2-yl-ethanone(cas: 88-15-3Quality Control of 1-Thiophen-2-yl-ethanone)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Quality Control of 1-Thiophen-2-yl-ethanone

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Safety of 2-(Thiophen-3-yl)-1,3-dioxolaneOn September 30, 2008 ,《The effects of pendant vs. fused thiophene attachment upon the luminescence lifetimes and electrochemistry of tris(2,2′-bipyridine)ruthenium(II) complexes》 was published in European Journal of Inorganic Chemistry. The article was written by Nurkkala, Lasse J.; Steen, Robert O.; Friberg, Henrik K. J.; Haeggstroem, Johanna A.; Bernhardt, Paul V.; Riley, Mark J.; Dunne, Simon J.. The article contains the following contents:

The electrochem. and photophys. properties for a range of tris(2,2′-bipyridine)ruthenium(II) complexes in which a thiophene substituent is attached to one of the bipyridine ligands by either a pendant or a fused mode were determined The fused mode of attachment eliminates torsional movement between the thiophene unit and the chelating bipyridine, thereby offering optimal overlap between the π-systems of the chelating unit and the attached thiophene unit. The electrochem. properties of these complexes are similar; however, the luminescence lifetimes and intensities (in CH3CN at room temperature) are correlated to the mode of attachment. The longest luminescence lifetime was observed for [Ru(bpy)2{4-(thiophen-2-yl)-2,2′-bipyridine}]2+ (3000 ns), as compared to the prototypic [Ru(bpy)3]2+ (1745 ns). This complex also had the highest quantum yield (0.045). In the four isomeric complexes, where the thiophene ring was fused to the b or c face of the pyridine ring, the lifetimes fell in the interval 275-1510 ns, and the quantum yield ranged between 0.0047 and 0.014. In addition to this study using 2-(Thiophen-3-yl)-1,3-dioxolane, there are many other studies that have used 2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3Safety of 2-(Thiophen-3-yl)-1,3-dioxolane) was used in this study.

2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3) is one of dioxolane. 1,3-Dioxolane derivatives are recognized as important motifs for the construction of numerous pharmacologically active molecules as antiviral, antifungal, anti-HIV, and adrenoreceptor antagonists.Safety of 2-(Thiophen-3-yl)-1,3-dioxolane

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Dantanarayana, Anura P.; DuPre, Brian; May, Jesse A.; Lynch, Vincent M. published their research in Journal of Heterocyclic Chemistry on February 28 ,1999. The article was titled 《A convenient synthesis of the novel 5H-thieno[2,3-e]-4,1,2-oxathiazepine ring system via an alkoxycarbenium ion intermediate》.Name: 2-(Thiophen-3-yl)-1,3-dioxolane The article contains the following contents:

3-(Methoxymethoxymethyl)-2-thiophenesulfonamides and 3-hydroxymethyl-N-methoxymethyl-2-thiophenesulfonamides were shown to undergo cyclization when treated under anhydrous acidic conditions to provide a novel 2,3-dihydro-5H-thieno[2,3-e]-4,1,2-oxathiazepine ring system. Incorporation of a primary sulfonamide group into position seven of the mol. provided compounds which inhibit human carbonic anhydrase II. In the part of experimental materials, we found many familiar compounds, such as 2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3Name: 2-(Thiophen-3-yl)-1,3-dioxolane)

2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3) is one of dioxolane. 1,3-Dioxolane derivatives are recognized as important motifs for the construction of numerous pharmacologically active molecules as antiviral, antifungal, anti-HIV, and adrenoreceptor antagonists.Name: 2-(Thiophen-3-yl)-1,3-dioxolane

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Dereu, Norbert; Piette, Jean Louis published their research in Bulletin de la Societe Chimique de France on December 31 ,1979. The article was titled 《o-Carbonylated (alkyltelluro)thiophenes and thiophenetellurenyl halides》.Product Details of 13250-82-3 The article contains the following contents:

Protected acylthiophenes I (R = H, Me) were lithiated (BuLi) and then treated with Te and MeI and BuBr to give tellurides II (R1 = Me, Bu). Also prepared were isomeric III (R = H, Me; R1 = Me, Bu). The results came from multiple reactions, including the reaction of 2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3Product Details of 13250-82-3)

2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3) is one of dioxolane. 1,3-Dioxolane derivatives are recognized as important motifs for the construction of numerous pharmacologically active molecules as antiviral, antifungal, anti-HIV, and adrenoreceptor antagonists.Product Details of 13250-82-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Related Products of 88-15-3In 2019 ,《A facile synthesis of highly fluorescent pyrido[2,3-d]pyrimidines and 1,8-naphthyridines via oxazine transformation and enaminic addition reactions》 appeared in Journal of the Iranian Chemical Society. The author of the article were El-Sayed, Hassan A.; Morsy, Hesham A.. The article conveys some information:

The synthesis and fluorescence properties of highly substituted bicyclic pyridine derivatives I (Ar = 4-ClC6H4; R = H, CH3, C6H5, 2,4-Cl2C6H3) and 2,2′-(1,3-phenylene)bis(5-(4-chlorophenyl)-7-(thien-2-yl)pyrido[2,3-d]pyrimidin-4(3H)-one), II (R1R2 = -(CH2)4-, -C(O)CH2C(CH3)2CH2-; R1 = C(O)CH3, C6H5; R2 = CH3) and III (R3 = H, SH) are described. The compounds 2-substituted-4-oxo-pyrido[2,3-d]pyrimidines I (Ar = 4-ClC6H4; R = H, CH3, C6H5, 2,4-Cl2C6H3) and 2,2′-(1,3-phenylene)bis(5-(4-chlorophenyl)-7-(thien-2-yl)pyrido[2,3-d]pyrimidin-4(3H)-one) resulted from the acylation reaction of α-aminonicotinonitrile IV with aroyl chlorides RC(O)Cl and isophthaloyl dichloride, di-Et malonate, Et morpholine-4-carboxylate, acetic anhydride or formic acid under solvent-free conditions. The [4 + 2] cyclocondensation and cycloaddition reactions of compound IV with formamide and ammonium thiocyanate tolerated the fused pyrimidines, III resp. Finally, the Friedlander-like reaction was applied for the synthesis of 1,8-naphthyridines II via reaction of compound IV with cyclohexanone, dimedone, acetyl acetone and benzyl Me ketone, resp., under AlCl3 catalysis. The fluorescence spectroscopic data of some synthesized compounds measured and significant results were observed The experimental process involved the reaction of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Related Products of 88-15-3)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Related Products of 88-15-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

The author of 《Iron-catalyzed oxidative functionalization of C(sp3)-H bonds under bromide-synergized mild conditions》 were Yu, Han; Zhao, Qixin; Wei, Zheyu; Wu, Zhikang; Li, Qi; Han, Sheng; Wei, Yongge. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. COA of Formula: C6H6OS The author mentioned the following in the article:

An efficient oxidation and functionalization of C-H bonds with an inorganic-ligand supported iron catalyst and hydrogen peroxide to prepare the corresponding ketones, e.g., 9H-fluoren-9-one was achieved using the bromide ion as a promoter. Preliminary mechanistic investigations indicated that the bromide ion can bind to FeMo6 to form a supramol. species (FeMo6.2Br), which can effectively catalyze the reaction. In the experiment, the researchers used many compounds, for example, 1-Thiophen-2-yl-ethanone(cas: 88-15-3COA of Formula: C6H6OS)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. COA of Formula: C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Gallazzi, Maria C.; Toscano, Francesca; Paganuzzi, Daniela; Bertarelli, Chiara; Farina, Alessandra; Zotti, Gianni published an article in Macromolecular Chemistry and Physics. The title of the article was 《Polythiophenes with unusual electrical and optical properties based on donor acceptor alternance strategy》.Computed Properties of C7H8O2S The author mentioned the following in the article:

The strategy of donor-acceptor alternation was adopted to reduce the energy gap in substituted polythiophenes; energy gaps down to 1.2 eV were obtained, which is a very low value in the class of polythiophenes. Alkoxy groups and dicyanoethenyl groups were used to prepare electron-rich and electron-poor thiophene units. The copolymers were obtained by coupling reaction methods (Suzuki) and by oxidative chem. and electrochem. polymerization of an opportunely designed substituted terthiophene. X-ray studies and spectroscopic data on the copolymers evidenced that the dicyanoethenyl group as substituent was rather steric demanding and susceptible of side reactions also preventing the n-doping of the material. The conductivity behavior was unusual but compatible with localized charge carriers. The experimental part of the paper was very detailed, including the reaction process of 2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3Computed Properties of C7H8O2S)

2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3) is one of dioxolane. 1,3-Dioxolane derivatives are recognized as important motifs for the construction of numerous pharmacologically active molecules as antiviral, antifungal, anti-HIV, and adrenoreceptor antagonists.Computed Properties of C7H8O2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem