Category: 90407-16-2

Electric Literature of 90407-16-2, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 90407-16-2, Name is 7-Chloro-1-benzothiophene-2-carboxylic acid, molecular formula is C9H5ClO2S. In a Patent£¬once mentioned of 90407-16-2

SALTS FOR THE PRODUCTION OF PHARMACEUTICAL PREPARATIONS

The object of the invention relates to the salts of encenicline formed with inorganic and organic acids of general formula (I), as well as to the use of these for the production of pharmaceutical preparations primarily suitable for the treatment of diseases involving cognitive disorder (schizophrenia, Alzheimer’s disease).

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 90407-16-2. In my other articles, you can also check out more blogs about 90407-16-2

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Recommanded Product: 7-Chloro-1-benzothiophene-2-carboxylic acid, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 90407-16-2, name is 7-Chloro-1-benzothiophene-2-carboxylic acid. In an article£¬Which mentioned a new discovery about 90407-16-2

Discovery of a new series of potent and selective linear tachykinin NK 2 receptor antagonists

Starting from 1 (MEN 14268), a selective tachykinin NK2 receptor antagonist with an interesting in vitro pharmacological profile, a family of numerous antagonists was obtained through an optimization process focused on iterated structural modifications. The effects of the introduction of a wide variety of substituents on the lipophilic aromatic part of the molecule and the modulation of the structural constraint through the insertion of different achiral alpha,alpha-dialkylamino acids were investigated. In particular, aromatic and benzofused heteroaromatic moieties were introduced at the pseudo-N-terminal residue to replace the 2-benzothiophene moiety, and a systematic investigation of the best positioning of substituents onto the aromatic platform was reported for the benzothiophene core. Studies on the modulation of the length and the rigidity of the hydrophilic pseudo-C-terminal pendant are presented. Many heteroaliphatic groups are well tolerated by the receptor in this part of the ligand. The product 48f (MEN15596), bearing a methyl substituent on the benzothiophene and a tetrahydropyranylmethylpiperidine pendant, was finally selected for its good in vivo activity after intravenous, intraduodenal, and oral administration in guinea pigs.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 90407-16-2, help many people in the next few years.Recommanded Product: 7-Chloro-1-benzothiophene-2-carboxylic acid

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Chemistry is traditionally divided into organic and inorganic chemistry. COA of Formula: C9H5ClO2S, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 90407-16-2

Optimized synthesis and solid state investigations on the drug candidate encenicline hydrochloride

For the production of drug substances a robust, scalable process delivering the active pharmaceutical ingredient (API) in excellent chemical and polymorphic purity is required. For this purpose we developed a novel imidazole-mediated one-pot procedure for the preparation of encenicline hydrochloride monohydrate, which crystallizes directly from the reaction mixture as pure non-hygroscopic polymorph (Form I). Solid state studies revealed a series of additional new physical forms for which crystal structures have been determined by single crystal X-ray diffraction.

If you are interested in 90407-16-2, you can contact me at any time and look forward to more communication. COA of Formula: C9H5ClO2S

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Related Products of 90407-16-2, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.90407-16-2, Name is 7-Chloro-1-benzothiophene-2-carboxylic acid, molecular formula is C9H5ClO2S. In a article£¬once mentioned of 90407-16-2

ANTIPRURITIC AGENT

An antipruritic which exerts an antipruritic effect based on a novel action mechanism and is effective for pruritus. The antipruritic contains as an effective ingredient a compound which activates a central type nicotinic acetylcholine receptor.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 90407-16-2

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

90407-16-2, Name is 7-Chloro-1-benzothiophene-2-carboxylic acid, belongs to benzothiophene compound, is a common compound. Computed Properties of C9H5ClO2SIn an article, once mentioned the new application about 90407-16-2.

CLEANING COMPOSITION AND METHOD OF MANUFACTURING METAL WIRING USING THE SAME

A cleaning composition includes about 0.01 to about 5 wt % of a chelating agent; about 0.01 to about 0.5 wt % of an organic acid; about 0.01 to about 1.0 wt % of an inorganic acid; about 0.01 to about 5 wt % of an alkali compound; and deionized water.

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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Application In Synthesis of 7-Chloro-1-benzothiophene-2-carboxylic acid, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 90407-16-2, Name is 7-Chloro-1-benzothiophene-2-carboxylic acid, molecular formula is C9H5ClO2S

PROCESS FOR THE PREPARATION OF ENCENICLINE FROM 7-CHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID CHLORIDE AND (R)-QUINUCLIDIN-3-AMINE IN THE PRESENCE OF IMIDAZOLE

The present invention relates to a process for the preparation of an amide from a carboxylic acid chloride and an organic molecule comprising both a primary amine group and a tertiary amine group, wherein the nitrogen atom of the tertiary amine group is comprised in a non-aromatic heterocycle and wherein the amide bond forms selectively with the primary amine group, comprising the step of reacting the carboxylic acid chloride with an organic molecule comprising both the primary amine group and the tertiary amine group, in the presence of imidazole. This is particularly useful in the preparation of amides from quinuclidin-3-amine, such as for the preparation of encenicline ((R) -7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide) from 7-chloro-benzo[b]thiophene-2-carboxylic acid chloride and (R)- quinuclidin-3-amine in the presence of imidazole. Encenicline is a nicotinic acetylcholine receptor agonist useful as a neuromodulator for the treatment of e.g. cognitive impairment, schizophrenia and Alzheimer’s disease.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Application In Synthesis of 7-Chloro-1-benzothiophene-2-carboxylic acid, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 90407-16-2

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Application In Synthesis of 7-Chloro-1-benzothiophene-2-carboxylic acid. Introducing a new discovery about 90407-16-2, Name is 7-Chloro-1-benzothiophene-2-carboxylic acid

7-Substituted Benzothiophenes and 1,2-Benzisothiazoles. Part 2. Chloro and Nitro Derivatives

The 7-chloro and 7-nitro derivatives of benzothiophene and 1,2-benzisothiazole have been prepared from readily available precursors, which for each substituent are common to both ring systems. 7-Chlorobenzothiophene has been obtained from 3-chloro-2-mercaptobenzoic acid via 7-chlorobenzothiophen-3(2H)-one, or from 2,3-dichlorobenzaldehyde, either via beta-(2,3-dichlorophenyl)-alpha-mercaptoacrylic acid (16) or, preferably, via 7-chlorobenzothiophene-2-carboxylic acid.Hexamethylphosphoric triamide is a particularly useful solvent in which to effect the selective nucleophilic replacement of the 2-chloro substituent in 2,3-dichlorobenzaldehyde. 7-Chloro-1,2-benzisothiazole is available by treatment of 3-chloro-2-mercaptobenzaldehyde with chloramine (57percent), or by heating 2,3-dichlorobenzaldehyde with sulphur and aqueous ammonia (46percent). 7-Nitrobenzothiophene has been obtained by treatment of 2-bromo-3-nitrobenzaldehyde with mercaptoacetic acid under alkaline conditions, followed by decarboxylation of the resulting 2-carboxylic acid.Cyclisation of 2-(n- or t-butylthio)-3-nitrobenzaldoxime with polyphosphoric acid gives 7-nitro-1,2-benzisothiazole in high yield. 3-Nitro-2-t-bytylthiobenzaldehyde behaves unexpectedly with chloramine, to give what is believed to be 7-nitro-2-t-butyl-1,2-benzothiazolium chloride (24) (73percent).

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of 7-Chloro-1-benzothiophene-2-carboxylic acid, you can also check out more blogs about90407-16-2

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem