Category: 88-15-3

Motokura, Ken; Ozawa, Nao; Sato, Risako; Manaka, Yuichi; Chun, Wang-Jae published an article in 2021. The article was titled 《Porous FeO(OH) Dispersed on Mg-Al Hydrotalcite Surface for One-Pot Synthesis of Quinoline Derivatives》, and you may find the article in ChemCatChem.Synthetic Route of C6H6OS The information in the text is summarized as follows:

The use of ubiquitous elements such as iron instead of expensive precious metals as catalysts is one goal toward realizing environmentally benign synthetic chem. Here, we report that porous FeO(OH) dispersed on Mg-Al hydrotalcite acts as a bifunctional heterogeneous catalyst in the one-pot synthesis of 2-substituted quinoline derivatives through dehydrogenative oxidation-cyclization reactions. The catalyst was prepared by a simple grafting method using FeCl3 and Mg-Al hydrotalcite. The prepared porous FeO(OH) possesses a higher surface area than those previously reported for α-FeO(OH) particles. The one-pot quinoline synthesis proceeded effectively under non-noble-metal catalysis in air without requiring addnl. homogeneous bases or solvents. The results came from multiple reactions, including the reaction of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Synthetic Route of C6H6OS)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Synthetic Route of C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《A metal-free heterogeneous photocatalyst for the selective oxidative cleavage of C=C bonds in aryl olefins via harvesting direct solar energy》 was written by Zhang, Yu; Hatami, Nareh; Lange, Niklas Simon; Ronge, Emanuel; Schilling, Waldemar; Jooss, Christian; Das, Shoubhik. Computed Properties of C6H6OS And the article was included in Green Chemistry in 2020. The article conveys some information:

A mild and efficient protocol was developed using polymeric carbon nitrides (PCN) as metal-free heterogeneous photocatalysts to convert various olefins into the corresponding carbonyls such as R1C(O)R2 [R1 = Ph, 4-MeC6H4, 2-pyridyl, etc.; R2 = H, Me, Ph, etc.]. Later, this catalyst was applied in the gram scale synthesis of pharmaceutical drugs using direct solar energy. Detailed mechanistic studies revealed the actual role of oxygen, the catalyst and the light source. In the part of experimental materials, we found many familiar compounds, such as 1-Thiophen-2-yl-ethanone(cas: 88-15-3Computed Properties of C6H6OS)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Computed Properties of C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《A Phosphine-Free Manganese Catalyst Enables Stereoselective Synthesis of (1 + n)-Membered Cycloalkanes from Methyl Ketones and 1,n-Diols》 was published in ACS Catalysis in 2020. These research results belong to Jana, Akash; Das, Kuhali; Kundu, Abhishek; Thorve, Pradip Ramdas; Adhikari, Debashis; Maji, Biplab. Recommanded Product: 88-15-3 The article mentions the following:

Herein, we report the stereoselective synthesis of (1 + n)-membered cycloalkane from Me ketone and 1,n-diol. A manganese(I) complex bearing a phosphine-free ligand catalyzed the reaction, which involved the formation of two C-C bonds via a sequence of intermol.- and intramol.-borrowing hydrogenation reactions. It produces 2 mol of water as the sole byproduct, making the process atom economical and environmentally benign. Multisubstituted cycloalkanes were obtained in good to excellent yields with very high selectivities. A thorough mechanistic anal. by high-level DFT computation rationalizes the choice of the pincer and establishes the role of hemilability of the ligand for this efficient transformation. In the part of experimental materials, we found many familiar compounds, such as 1-Thiophen-2-yl-ethanone(cas: 88-15-3Recommanded Product: 88-15-3)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Recommanded Product: 88-15-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

In 2019,Food Chemistry included an article by Zhao, Jian; Wang, Tianze; Xie, Jianchun; Xiao, Qunfei; Cheng, Jie; Chen, Feng; Wang, Shi; Sun, Baoguo. Category: benzothiophene. The article was titled 《Formation mechanism of aroma compounds in a glutathione-glucose reaction with fat or oxidized fat》. The information in the text is summarized as follows:

Glutathione and glucose with or without chicken fat/oxidized chicken fat were thermally reacted for generation of stewed meat-like aroma, where 42 sulfur-containing odorants were identified by gas chromatog.-mass spectrometry (GC-MS) and gas chromatog.-olfactometry (GC-O). The observed effects or interactions on meat flavor formation due to the fats were similar to previous reports of cysteine-reducing sugar reactions. Carbohydrate module labeling approach demonstrated ten alkyl chain compounds were indeed resulted from the lipid degradation-Maillard reaction interactions, whereas the fats had little effect on formation pathways of compounds only derived from the Maillard reaction. Formation pathways of 26 potent aroma compounds were proposed, particularly, involving two benzene derivatives and seven complex thiophenes. Notably, it was found for the first time just 2-ethylthiophene could result from both an intact skeleton of glucose and the lipid degradation product of 2,4-hexadienal, and the carbohydrate modules methylglyoxal and hydroxyacetone could arise from the glutamic acid of GSH. In the experimental materials used by the author, we found 1-Thiophen-2-yl-ethanone(cas: 88-15-3Category: benzothiophene)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Category: benzothiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

In 2019,Synthesis included an article by Dar’in, Dmitry; Kantin, Grigory; Krasavin, Mikhail. COA of Formula: C6H6OS. The article was titled 《Practical Application of the Aqueous ‘Sulfonyl-Azide-Free’ (SAFE) Diazo Transfer Protocol to Less α-C-H Acidic Ketones and Esters》. The information in the text is summarized as follows:

The earlier described ‘sulfonyl-azide-free (SAFE) protocol for diazo transfer to CH-acidic 1,3-dicarbonyl compounds (and their similarly activated congeners) has been extended to the less reactive monocarbonyl substrates, which previously required a sep. activation step. Formylation in situ, followed by the addition of an optimized amount of the ‘SAFE cocktail’ (obtained by mixing sodium azide, potassium carbonate, and m-carboxybenzenesulfonyl chloride in water) led to the formation of the desired diazo compounds, which were isolated by extraction in moderate to excellent yields, and, in most cases, with no need for addnl. purification1-Thiophen-2-yl-ethanone(cas: 88-15-3COA of Formula: C6H6OS) was used in this study.

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. COA of Formula: C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Xu, Jun; Huang, Lin; He, Lei; Ni, Zhigang; Shen, Jiabin; Li, Xiaoling; Chen, Kaixian; Li, Wanmei; Zhang, Pengfei published their research in Green Chemistry in 2021. The article was titled 《A combination of heterogeneous catalysis and photocatalysis for the olefination of quinoxalin-2(1H)-ones with ketones in water: a green and efficient route to (Z)-enaminones》.Recommanded Product: 88-15-3 The article contains the following contents:

Herein, a novel aqueous reaction for the olefination of quinoxalin-2(1H)-ones I (R1 = H, 5-Me, 6-OMe, 6,7-Cl2, etc.; R2 = H, Me, cyclohexylmethyl, allyl, Ph, 2,6-F2C6H3CH2, etc.) with ketones R3C(O)CH2R4 [R3 = Me, cyclopropyl, Ph, 3-thienyl, etc., R4 = H; R3R4 = (CH2)3, CH(cyclopentyl)CH2CH2] through a combinational strategy is described. This reaction features very mild conditions using a simple and cheap catalyst for the synthesis of (Z)-enaminones II in moderate-to-good yields. Such a methodol. successfully combines the heterogeneous Mannich reaction with photocatalysis, and provides a green and practical approach for the synthesis of potentially bioactive (Z)-enaminones with a 3,4-dihydroquinoxalin-2(1H)-one skeleton. The experimental part of the paper was very detailed, including the reaction process of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Recommanded Product: 88-15-3)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Recommanded Product: 88-15-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

The author of 《Four-component thiazole formation from simple chemicals under metal-free conditions》 were Jiang, Jingjing; Huang, Huawen; Deng, Guo-Jun. And the article was published in Green Chemistry in 2019. Reference of 1-Thiophen-2-yl-ethanone The author mentioned the following in the article:

Multi-component reactions for the synthesis of polysubstituted thiazoles from simple chems. were described. Under metal-free reaction conditions, cheap and easily available ketones, aldehydes, ammonium salt and elemental sulfur were self-assembled to provided entries to three thiazoles in moderate to good yield with a range of functionalities tolerated. In addition to this study using 1-Thiophen-2-yl-ethanone, there are many other studies that have used 1-Thiophen-2-yl-ethanone(cas: 88-15-3Reference of 1-Thiophen-2-yl-ethanone) was used in this study.

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Reference of 1-Thiophen-2-yl-ethanone

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

In 2022,Paganelli, Stefano; Tassini, Riccardo; Piccolo, Oreste published an article in ChemistrySelect. The title of the article was 《Sustainable Synthesis of Aryl and Heteroaryl Aldehydes》.Recommanded Product: 1-Thiophen-2-yl-ethanone The author mentioned the following in the article:

In this paper, authors’ focused on the synthesis of some (hetero)aromatic aldehydes, used either as industrial flavor/fragrances of com. interest, such as heliotropine, or as key intermediates for the preparation of some APIs and of other fragrances such as lioral and helional, by reductive carbonylation of halo derivative precursors. In order to carry out an easier and more applicable process, hydrogen donors, instead of gaseous flammable and explosive hydrogen, and recyclable phosphine free low metal content catalysts, were employed. In the experiment, the researchers used 1-Thiophen-2-yl-ethanone(cas: 88-15-3Recommanded Product: 1-Thiophen-2-yl-ethanone)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Recommanded Product: 1-Thiophen-2-yl-ethanone

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

In 2019,Tetrahedron Letters included an article by Sahoo, Debasis; Sarkar, Sohini; Jana, Samaresh. Recommanded Product: 88-15-3. The article was titled 《A simple synthesis of ketone from carboxylic acid using tosyl chloride as an activator》. The information in the text is summarized as follows:

An effective process for the conversion of carboxylic acids to ketones was discovered. In this process, carboxylic acid was activated using p-toluene sulfonyl group. Under the optimized condition, aromatic, aliphatic heteroaromatic carboxylic acids was proved to be good substrates for this methodol. The byproduct of this reaction can be removed very easily during work up process. Also, one equivalent of organometallic reagent was sufficient to complete this transformation. In addition to this study using 1-Thiophen-2-yl-ethanone, there are many other studies that have used 1-Thiophen-2-yl-ethanone(cas: 88-15-3Recommanded Product: 88-15-3) was used in this study.

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Recommanded Product: 88-15-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《Design and Syntheses of Palladium Complexes of NNN/CNN Pincer Ligands: Catalyst for Cross Dehydrogenative Coupling Reaction of Heteroarenes》 was written by Shinde, Vikki N.; Bhuvanesh, Nattamai; Kumar, Anil; Joshi, Hemant. Synthetic Route of C6H6OS And the article was included in Organometallics in 2020. The article conveys some information:

This report describes simple syntheses of a new class of Pd(II) pincer complexes having NNN and CNN coordination modes. The new complexes were fully characterized with the help of 1H and 13C{1H} NMR, HRMS, and IR spectroscopy. The structure and bonding modes of complexes were further authenticated with the help of single-crystal x-ray diffraction. Thermally robust and moisture-/air-insensitive Pd pincer complexes C1-C4 were used as catalysts for cross dehydrogenative coupling (CDC) reactions of two heteroarenes and are very efficient. The catalyst was successful in activating the C-H bond of a variety of heteroarenes, including benzimidazole, imidazole, benzothiazole, imidazopyridine, thiophene, and furan, with only 1.0 mol % of catalyst, achieving excellent yields of the coupled products. The catalyst showed excellent tolerance toward functional groups such as CHO, COMe, COOMe, COOEt, CONHPh, Me, CN, Br, and Cl. Further, the catalyst is reusable up to four reaction cycles with only a minor loss in its efficiency. The mechanism of the CDC reaction was studied through control experiments, and probably a Pd acetate analog of the NNN pincer ligand (C5) is the active catalyst. The experimental process involved the reaction of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Synthetic Route of C6H6OS)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Synthetic Route of C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem