Category: 88-15-3

《Palladium-Catalyzed Dual Ligand-Enabled Alkylation of Silyl Enol Ether and Enamide under Irradiation: Scope, Mechanism, and Theoretical Elucidation of Hybrid Alkyl Pd(I)-Radical Species》 was written by Zhao, Bin; Shang, Rui; Wang, Guang-Zu; Wang, Shaohong; Chen, Hui; Fu, Yao. Computed Properties of C6H6OS And the article was included in ACS Catalysis in 2020. The article conveys some information:

We report herein that a palladium catalyst in combination with a dual phosphine ligand system catalyzes alkylation of silyl enol ether and enamide with a broad scope of tertiary, secondary, and primary alkyl bromides under mild irradiation conditions by blue light-emitting diodes. The reactions effectively deliver α-alkylated ketones and α-alkylated N-acyl ketimines, and it is difficult to prepare the latter by other methods in a stereoselective manner. The α-alkylated N-acyl ketimine products can be further subjected to chiral phosphoric acid-catalyzed asym. reduction with Hantzsch ester to deliver chiral N-acyl-protected α-arylated aliphatic amines in high enantioselectivity up to 99% ee, thus providing a method for facile synthesis of chiral α-arylated aliphatic amines, which are of importance in medicinal chem. research. The N-acetyl ketimine product also reacted smoothly with various types of Grignard reagents to afford sterically bulky N-acetyl α-tertiary amines in high yields. Theor. studies in combination with exptl. investigation provide understanding of the reaction mechanism with respect to the dual ligand effect and the irradiation effect in the catalytic cycle. The reaction is suggested to proceed via a hybrid alkyl Pd(I)-radical species generated by inner-sphere electron transfer of phosphine-coordinated Pd(0) species with alkyl bromide. This intriguing hybrid alkyl Pd(I)-radical species is elucidated by theor. calculation to be a triplet species coordinated by three phosphine atoms with a distorted tetrahedral geometry, and spin prohibition rather than metal-to-ligand charge transfer contributes to the kinetic stability of the hybrid alkyl Pd(I)-radical species to impede alkyl recombination to generate Pd(II) alkyl intermediate. The experimental part of the paper was very detailed, including the reaction process of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Computed Properties of C6H6OS)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Computed Properties of C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《Nanostructured N doped TiO2 efficient stable catalyst for Kabachnik-Fields reaction under microwave irradiation》 was written by Kunde, Sachin P.; Kanade, Kaluram G.; Karale, Bhausaheb K.; Akolkar, Hemant N.; Arbuj, Sudhir S.; Randhavane, Pratibha V.; Shinde, Santosh T.; Shaikh, Mubarak H.; Kulkarni, Aniruddha K.. Reference of 1-Thiophen-2-yl-ethanone And the article was included in RSC Advances in 2020. The article conveys some information:

Herein, we report nitrogen-doped TiO2 (N-TiO2) solid-acid nanocatalysts with heterogeneous structure employed for the solvent-free synthesis of α-aminophosphonates through Kabachnik-Fields reaction. N-TiO2 were synthesized by direct amination using triethylamine as a source of nitrogen at low temperature and optimized by varying the volume ratios of TiCl4, methanol, water, and triethylamine, under identical conditions. An X-ray diffraction (XRD) study showed the formation of a rutile phase and the crystalline size is 10 nm. The nanostructural features of N-TiO2 were examined by HR-TEM anal., which showed they had rod-like morphol. with a diameter of 7 to 10 nm. Diffuse reflectance spectra show the extended absorbance in the visible region with a narrowing in the band gap of 2.85 eV, and the high resolution XPS spectrum of the N 1s region confirmed successful doping of N in the TiO2 lattice. More significantly, we found that as-synthesized N-TiO2 showed significantly higher catalytic activity than com. available TiO2 for the synthesis of a novel series of α-amino phosphonates via Kabachnik-Fields reaction under microwave irradiation conditions. The improved catalytic activity is due to the presence of strong and Bronsted acid sites on a porous nanorod surface. This work signifies N-TiO2 is an efficient stable catalyst for the synthesis of α-aminophosphonate derivatives In the experimental materials used by the author, we found 1-Thiophen-2-yl-ethanone(cas: 88-15-3Reference of 1-Thiophen-2-yl-ethanone)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Reference of 1-Thiophen-2-yl-ethanone

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《Visible-Light-Promoted Photocatalyst-Free Hydroacylation and Diacylation of Alkenes Tuned by NiCl2·DME》 was written by Zhao, Xinxin; Li, Bing; Xia, Wujiong. Product Details of 88-15-3This research focused onvisible light hydroacylation diacylation alkene nickel chloride glyme; ketone synthesis; dicarbonyl compound synthesis. The article conveys some information:

Herein, we describe a visible light-promoted hydroacylation strategy that facilitates the preparation of ketones from alkenes and 4-acyl-1,4-dihydropyridines via an acyl radical addition and hydrogen atom transfer pathway under photocatalyst-free conditions. The efficiency was highlighted by wide substrate scope, good to high yields, successful scale-up experiments, and expedient preparation of highly functionalized ketone derivatives In addition, this protocol allows for the synthesis of 1,4-dicarbonyl compounds through alkene diacylation in the presence of NiCl2·DME. In the part of experimental materials, we found many familiar compounds, such as 1-Thiophen-2-yl-ethanone(cas: 88-15-3Product Details of 88-15-3)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Product Details of 88-15-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《Oxidative Kinetic Resolution of Acyclic Amines Based on Equilibrium Control》 was published in Organic Letters in 2020. These research results belong to Saito, Kodai; Miyashita, Hiromitsu; Ito, Yui; Yamanaka, Masahiro; Akiyama, Takahiko. Reference of 1-Thiophen-2-yl-ethanone The article mentions the following:

An oxidative kinetic resolution of racemic acyclic amines was developed using an imine derivative as the resolving reagent and chiral phosphoric acid as the catalyst to give enantiomers in good yields with high to excellent enantioselectivities. The key to success of the title reaction was the equilibrium control by adjusting the ratio of the resolving reagent and unique enantiodivergence was observed depending on the equilibrium displacement. In the experiment, the researchers used many compounds, for example, 1-Thiophen-2-yl-ethanone(cas: 88-15-3Reference of 1-Thiophen-2-yl-ethanone)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Reference of 1-Thiophen-2-yl-ethanone

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

The author of 《Acid-Catalyzed Condensation of o-Phenylenediamines and o-Aminophenols with α-Oxodithioesters: A Divergent and Regioselective Synthesis of 2-Methylthio-3-aryl/Heteroarylquinoxalines and 2-Acylbenzoxazoles》 were Kiran, Kuppalli R.; Swaroop, Toreshettahally R.; Sukrutha, Kodipura P.; Shruthi, Jeegundipattana B.; Anil, Seegehally M.; Rangappa, Kanchugarakoppal S.; Sadashiva, Maralinganadoddi P.. And the article was published in Synthesis in 2019. Formula: C6H6OS The author mentioned the following in the article:

O-Phenylenediamines and o-aminophenols were reacted with α-oxodithioesters in a highly regioselective fashion to give 2-methylthio-3-aryl/heteroarylquinoxalines I (R = C6H5, 2-thienyl, 4-FC6H4, etc.; R1 = H, 6-Br, 6-CF3, 6-NO2) and 2-acylbenzoxazoles II (R = C6H5, 4-OMeC6H4, 4-ClC6H4, etc.; R1 = H, 5-Me, 5-NO2) in 55-94% and 45-86%, resp., in the presence of p-toluenesulfonic acid catalyst. Control experiments involving reaction of aniline with a α-oxodithioester indicated that the thiocarbonyl group is more reactive than the carbonyl group. Based on this, probable mechanisms for the formation of quinoxalines and benzoxazoles are given. Biol. targets of the quinoxalines and benzoxazoles were identified by bioinformatics. It was found that quinoxalines have good binding affinity with human dual-specificity tyrosine-phosphorylation-regulated kinase 1A and benzoxazoles with human carboxylesterase. After reading the article, we found that the author used 1-Thiophen-2-yl-ethanone(cas: 88-15-3Formula: C6H6OS)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Formula: C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

In 2022,Virgili, Tersilla; Ganzer, Lucia; Botta, Chiara; Squeo, Benedetta Maria; Pasini, Mariacecilia published an article in Molecules. The title of the article was 《Asymmetric AZA-BODIPY with Optical Gain in the Near-Infrared Region》.Synthetic Route of C6H6OS The author mentioned the following in the article:

In recent years, there has been a lot of interest in the development of organic compounds emitting in the near-IR (NIR) region due to their stimulating applications, such as biosensing and light detection and ranging (LiDAR). Moreover, a lot of effort has been devoted to finding organic emitters with optical gain in the NIR region for lasing applications. In this paper, we present the ultrafast spectroscopy of an asym. AZA-BODIPY mol. that shows relevant photophys. changes moving from a diluted solution to a concentrated solution and to a spin-coated film. The diluted solution and the spin-coated film show a bleaching band and a stimulated emission band in the visible region, while the very concentrated solution displays a broad (150 nm) and long-living (more than 400 ps) optical gain band in the NIR region, centered at 900 nm. Our results pave the way for a new organic laser system in a near-IR spectral region. The results came from multiple reactions, including the reaction of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Synthetic Route of C6H6OS)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Synthetic Route of C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《Synthesis of an Air-Stable Pd(0) Catalyst Bearing Donor and Acceptor Phosphine Ligands》 was published in Organometallics in 2020. These research results belong to Sato, Ryota; Kanbara, Takaki; Kuwabara, Junpei. Synthetic Route of C6H6OS The article mentions the following:

The authors synthesized a new Pd(0) complex bearing π-acceptor ligands and a σ-donor ligand and confirmed that it exhibits high air stability and catalytic activity in direct arylation reactions. Also, stoichiometric reactions of the complex revealed that the σ-donor ligand does not dissociate from the Pd center.1-Thiophen-2-yl-ethanone(cas: 88-15-3Synthetic Route of C6H6OS) was used in this study.

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Synthetic Route of C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《Efficient and Environmentally Friendly Adsorbent Based on β-Ketoenol-Pyrazole-Thiophene for Heavy-Metal Ion Removal from Aquatic Medium: A Combined Experimental and Theoretical Study》 was published in ACS Omega in 2020. These research results belong to Tighadouini, Said; Radi, Smaail; El Massaoudi, Mohamed; Lakbaibi, Zouhair; Ferbinteanu, Marilena; Garcia, Yann. Name: 1-Thiophen-2-yl-ethanone The article mentions the following:

A new sustainable and environmentally friendly adsorbent based on a β-ketoenol-pyrazole-thiophene receptor grafted onto a silica surface was developed and applied to the removal of heavy-metal ions (Pb(II), Cu(II), Zn(II), and Cd(II)) from aquatic medium. The new material SiNPz-Th was well characterized and confirms the success of covalent binding of the receptor on the silica surface. The effect of environmental parameters on adsorption including pH, contact time, temperature, and the initial concentration were investigated. The maximum adsorption capacities of SiNPz-Th for Pb(II), Cu(II), Zn(II), and Cd(II) ions were 102.20, 76.42, 68.95, and 32.68 mg/g, resp., at 30 min and pH = 6. The adsorption isotherms, kinetics, and thermodn. process were investigated and showed efficiency and selectivity toward Pb(II) and good regeneration performance. D. functional theory, noncovalent-interaction, and quantum theory of atoms in mols. calculations were used to study and to gain a deeper understanding of both the adsorption mechanism and selectivity of metal ions onto the adsorbent. Accordingly, metal ions such as Pb(II), Cu(II), and Zn(II) were bidentate coordinated with the adsorbent by nitrogen and oxygen atoms of the Schiff base C=N and hydroxyl group -OH, resp., to form stable complexes. Whereas Cd(II) was coordinated in a monodentate fashion with oxygen atom of the hydroxyl group. Furthermore, the affinity of SiNPz-Th toward the metal ions was decreased in the order of Pb(II) > Cu(II) > Zn(II) > Cd(II), in good agreement with the exptl. results. All these results highlight that SiNPz-Th has good potential to be an advanced adsorbent for the removal of lead ions from real water. The experimental process involved the reaction of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Name: 1-Thiophen-2-yl-ethanone)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Name: 1-Thiophen-2-yl-ethanone

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

SDS of cas: 88-15-3In 2021 ,《Iron catalyzed metal-ligand cooperative approaches towards sustainable synthesis of quinolines and quinazolin-4(3H)-ones》 appeared in Tetrahedron. The author of the article were Mondal, Rakesh; Chakraborty, Gargi; Guin, Amit Kumar; Pal, Subhasree; Paul, Nanda D.. The article conveys some information:

Herein authors report simple, efficient, and economically affordable metal-ligand cooperative strategies for synthesizing quinolines and quinazolin-4(3H)-ones via dehydrogenative functionalization of alcs. Various polysubstituted quinolines and quinazolin-4(3H)-ones were prepared in good yields via dehydrogenative coupling of readily available alcs. with ketones and 2-aminobenzamides, resp. under air using a well-defined Fe(II)-catalyst, ([FeL1Cl2]) bearing a redox-active azo-aromatic pincer 2-((4-chlorophenyl), (diazenyl)-1,10-phenanthroline) (L1). Control experiments and mechanistic investigation disclose that the one-electron reduced mono-anionic species [1]- bearing an iron-stabilized azo-anion radical ligand catalyzes these reactions. Both iron and the redox-active arylazo ligand participate synergistically during the different steps of these catalytic reactions. In the experimental materials used by the author, we found 1-Thiophen-2-yl-ethanone(cas: 88-15-3SDS of cas: 88-15-3)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. SDS of cas: 88-15-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《Three Coordinated Organoaluminum Cation for Rapid and Selective Cyanosilylation of Carbonyls under Solvent-Free Conditions》 was written by Rawat, Sandeep; Bhandari, Mamta; Prashanth, Billa; Singh, Sanjay. Related Products of 88-15-3 And the article was included in ChemCatChem in 2020. The article conveys some information:

The well-defined three coordinated electronically unsaturated cationic organoaluminum complex [({(2,6-iPr2C6H3N)P(Ph2)}2N)AlMe]+ [MeB(C6F5)3]- (1), was used to catalyze the cyanosilylation of aldehydes and ketones under mild and solvent-free conditions. Also, catalyst 1 showed high chemoselective cyanosilylation of aldehydes over ketones, nitriles and olefins. The multinuclear NMR studies revealed that cyanosilylation proceeds via Lewis adduct formation between 1 and TMSCN thereby activating TMSCN (Si-CN bond) followed by nucleophilic attack of the carbonyl O at the Si center of the activated silane and formation of the product. In the part of experimental materials, we found many familiar compounds, such as 1-Thiophen-2-yl-ethanone(cas: 88-15-3Related Products of 88-15-3)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Related Products of 88-15-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem