Category: 67237-53-0

Metallaphotoredox-Enabled Intermolecular Carbobromination of Alkynes with Alkenyl Bromides was written by Yu, Wei;Jiao, Xiaorui;Fan, Yanmin;Zhu, Shengqing;Chu, Lingling. And the article was included in Advanced Synthesis & Catalysis in 2022.Quality Control of 3-Ethynylthiophene This article mentions the following:

A regioselective intermol. carbohalogenation of alkynes with alkenyl bromides enabled by dual photoredox and nickel catalysis was described. This dual protocol enabled an atom-economic access to a wide array of brominated 1,3-dienes from simple starting materials. Broad substrate scope and high regioselectivity were observed The synthetic utility was demonstrated and preliminary mechanistic studies were performed to elucidate the reaction pathway. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0Quality Control of 3-Ethynylthiophene).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Quality Control of 3-Ethynylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Boryl-Dictated Site-Selective Intermolecular Allylic and Propargylic C-H Amination was written by Liu, Yuan;Chen, Zhi-Hao;Li, Yin;Qian, Jiasheng;Li, Qingjiang;Wang, Honggen. And the article was included in Journal of the American Chemical Society in 2022.COA of Formula: C6H4S This article mentions the following:

For internal alkenes possessing two or more sets of electronically and sterically similar allylic protons, the site-selectivity for allylic C-H functionalization is fundamentally challenging. Previously, the neg. inductive effect from an electroneg. atom is effective for several inspiring regioselective C-H functionalization reactions. Yet, the use of an electropos. atom for a similar purpose remains to be developed. α-Aminoboronic acids and their derivatives found widespread applications. Their current syntheses rely heavily on functional group manipulations. Herein the authors report a boryl-directed intermol. C-H amination of allyl N-methyliminodiacetyl boronates (B(MIDA)s) and propargylic B(MIDA)s to give α-amino boronates with an exceptionally high level of site-selectivities (up to 300:1). A wide variety of highly functionalized secondary and tertiary α-amino boronates are formed in generally good to excellent yields, thanks to the mildness of the reaction conditions. The unsaturated double and triple bonds within the product leave room for further decorations. Mechanistic studies reveal that the key stabilization effect of the B(MIDA) moiety on its adjacent developing pos. charge is responsible for the high site-selectivity and that a closed transition state might be involved, as the reaction is fully stereoretentive. An activation effect of B(MIDA) is also found. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0COA of Formula: C6H4S).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.COA of Formula: C6H4S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Efficient Synthesis of Dipyrrolobenzenes and Dipyrrolopyrazines via Bidirectional Gold Catalysis: a Combined Synthetic and Photophysical Study was written by Heckershoff, Robin;Schnitzer, Tobias;Diederich, Tim;Eberle, Lukas;Kraemer, Petra;Rominger, Frank;Rudolph, Matthias;Hashmi, A. Stephen K.. And the article was included in Journal of the American Chemical Society in 2022.Product Details of 67237-53-0 This article mentions the following:

A straightforward synthesis to access meta/para-dipyrrolobenzenes I [R = R¹ = Ph, 2-naphthyl, 4-MeOC₆H₄, etc.; R³ = R⁴ = H, n-octyl], II [R⁵ = R⁶ = H, Ph, 2-H₂NC₆H₄, 2-BrC₆H₄] and para-dipyrrolopyrazines III [R⁷ = R⁸ = TIPS, Ph] in high yields using a bidirectional gold-catalyzed cyclization strategy. The versatility of reaction protocol was showcased by preparing dipyrroloarenes with different substituents, various functional groups, and in a multitude of substitution patterns. Furthermore, the dipyrroloarenes could be post-modified by N-alkylation to improve the solubility or bromination to yield precursors for further derivatization via cross-coupling. Investigation of the photophys. properties of the-mostly unprecedented-dipyrroloarenes I, II, III and dialkyne precursors were identified strong blue emitters such as the di-Ph meta-dipyrrolobenzene with a quantum yield of 98%. Moreover, changes in the solvent polarity or interactions with Lewis acids such as borane could be used to fine-tune the photophys. properties of the fluorophores. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0Product Details of 67237-53-0).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Product Details of 67237-53-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Facile synthesis of N²-substituted-1,2,3-triazole from aryl ethynylene and azide via a one-pot two-step strategy was written by Guan, Cong;Ji, Jian;Li, Zi;Wei, Qinghua;Wu, Xiang;Liu, Shunying. And the article was included in Tetrahedron in 2022.Electric Literature of C6H4S This article mentions the following:

An efficient one-pot two-step synthetic strategy to access highly selective N2-substituted-1,2,3-triazole from aryl ethynylenes, azides and furan has been developed via a radical transformation. 17 Examples of aryl ethynylene with various substituents were converted into their corresponding functionalized N2-substituted-1,2,3-triazole derivatives in good yields. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0Electric Literature of C6H4S).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Electric Literature of C6H4S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Phosphine-Based Hyper-Cross-Linked Polymer-Supported Neutral Gold(I) Complex as a Recyclable Catalyst for the Regioselective Hydration of Alkynes to Ketones was written by Shen, Lu;Han, Xingyou;Dong, Beixuan;Yang, Yong;Yang, Jiazhi;Li, Feng. And the article was included in ACS Applied Polymer Materials in 2022.Related Products of 67237-53-0 This article mentions the following:

A phosphine-based hyper-cross-linked polymer-supported neutral gold(I) complex, Au@HCPs-PPh₃, which was synthesized by incorporation of [(Me₂S)AuCl] into a phosphine-based hyper-cross-linked polymer, was proven to be an efficient and general heterogeneous catalyst for the regioselective hydration of a series of alkynes to ketones RC(O)Me [R = t-Bu, 4-MeC₆H₄, 4-BrC₆H₄, etc.]. Furthermore, the synthesized catalyst was recycled six times without an obvious decrease in the catalytic activity. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0Related Products of 67237-53-0).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Related Products of 67237-53-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis of Pyridine-SF₄-Isoxazolines Using the Functionality of trans-Tetrafluoro-λ⁶-sulfanyl Rodlike Linkers was written by Maruno, Koki;Hada, Kenshiro;Sumii, Yuji;Nagata, Osamu;Shibata, Norio. And the article was included in Organic Letters in 2022.Synthetic Route of C6H4S This article mentions the following:

The tetrafluoro-λ⁶-sulfanyl (SF₄) moiety has been relatively undeveloped since its discovery in the 1970s. In this study, we synthesized pyridine-SF₄-isoxazolines, in which the two heterocycles are connected by a rodlike trans-SF₄ linker, via the regioselective 1,3-dipolar cycloaddition of pyridine-SF₄-alkynes and nitrones in the presence of triethylamine. SF₄ linkers are a viable alternative to para-substituted benzenes, alkynes, and bicyclo[1.1.1]pentyl derivatives in drug design, and pyridine-SF₄-isoxazolines have potential applications in drug development. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0Synthetic Route of C6H4S).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Synthetic Route of C6H4S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Combinatorial synthesis of new fluorescent scaffolds using click chemistry was written by Cleemann, Felix;Kum-Cheung, Wendy Loa;Karuso, Peter. And the article was included in Tetrahedron Letters in 2022.COA of Formula: C6H4S This article mentions the following:

Azides and acetylenes are bio-orthogonal functional groups that can be readily coupled using copper(I)- or ruthenium(II)- catalyzed 1,3-dipolar cycloaddition reactions. Using non-fluorescent aromatic azides and aromatic acetylenes, covering a range of electron rich and poor building blocks, the Huisgen cycloaddition afford 1,4-disubstituted or 1,5-disubstituted 1,2,3-triazoles. Using a combinatorial approach by running reaction in parallel in polypropylene 96-well plates we discovered several new fluorescent 1,2,3-triazoles scaffolds. These compounds show diverse interactions with biomols. that could find applications in biol. in, for example, fluorescence microscopy or biomol. quantification. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0COA of Formula: C6H4S).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.COA of Formula: C6H4S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Nitrogen-doped mesoporous carbon single crystal-based Ag nanoparticles for boosting mild CO₂ conversion with terminal alkynes was written by Zhang, Zhongzheng;Shi, Jialin;Zhu, Tianyang;Zhang, Lina;Wei, Wei. And the article was included in Journal of Colloid and Interface Science in 2022.SDS of cas: 67237-53-0 This article mentions the following:

Fabrication of efficient heterogeneous catalysts with high turnover frequency (TOF) is intriguing for rapid and scalable CO₂ conversion under mild conditions, but it still faces some challenges due to use of some bulky and irregular supports causing inaccessible inner pores and insufficient utilization of active sites. Herein, using a unique nitrogen-doped mesoporous single-crystal carbon (named IRFC) as a host for loading Ag nanoparticles for the first time, a series of Ag/IRFC catalysts with high TOF (8.7-22.3 h-1) were facilely prepared by a novel “impregnation and in-situ reduction” strategy. The neat morphol. and high porosity of IRFC with abundant N species, providing homogeneous surface, adequate space and anchoring sites for Ag immobilization, greatly facilitated the formation of highly-distributed ultrasmall Ag nanoparticles (2.3 nm). Meanwhile, smooth and short diffusion pathways were inherited from the ordered mesopores and small particle sizes of IRFC. Owing to these unparalleled structural features, the Ag/IRFC catalysts exhibited excellent catalytic activity, stability, and generality for mild CO₂ conversion even under diluted conditions. This work not only presents a novel catalyst for mild CO2 conversion, but also brings some inspirations to designing highly efficient catalysts using well-shaped supporting nanomaterials for direct utilization of low-concentration _CO2, such as flue gas. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0SDS of cas: 67237-53-0).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.SDS of cas: 67237-53-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Enantioselective Trost alkynylation with 2E,4E-5-bromo-2,4-pentadienal was written by Ervik, Karina;Vidar Hansen, Trond. And the article was included in Tetrahedron Letters in 2022.SDS of cas: 67237-53-0 This article mentions the following:

The synthetically useful aldehyde 2E,4E-5-bromo-2,4-pentadienal were subjected to the enantioselective Trost alkynylation protocol, yielding highly functionalized propargylic secondary alcs. in an enantioselective manner. In most cases, the isolated yields and enantiomeric excess of the products were modest to high, but several products were formed in both high yields and enantiomeric excess. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0SDS of cas: 67237-53-0).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.SDS of cas: 67237-53-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Palladium-Catalyzed Carbonylative Sonogashira/Annulation Reaction: Synthesis of Indolo[1,2-b]isoquinolines was written by Li, Lin;Liu, Xin-Lian;Qi, Zhuang;Yang, Ai-Hua;Ma, Ai-Jun;Peng, Jin-Bao. And the article was included in Organic Letters in 2022.Category: benzothiophene This article mentions the following:

A palladium-catalyzed carbonylative Sonogashira/annulation reaction for the synthesis of indolo[1,2-b]isoquinolines I [Ar = Ph, 4-MeC₆H₄, 3,4-di-MeOC₆H₃, etc.; R¹ = H, 3-F, 2-F, 2-Cl, 3-Cl, 3-Me; R² = H, 8-F, 9-Me ] was developed. Tetracyclic 6/5/6/6 indoline skeletons I were synthesized in moderate to good yields from easily available 2-bromo-N-(2-iodophenyl)benzamides and terminal alkynes. Notably, this efficient methodol. established three C-C bonds and a C-N bond through a one-step transformation and provided a new method for the synthesis of indolo[1,2-b]isoquinoline derivatives I. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0Category: benzothiophene).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Category: benzothiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem