Li, Xiaochuan et al. published their research in Molecular Crystals and Liquid Crystals in 2019 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.COA of Formula: C6H8S

Photochromic reactivity induced by electron distribution: active or inactive was written by Li, Xiaochuan;Wang, Yaxin;Jia, Caixia;Kim, Hyorim;Son, Young-A.. And the article was included in Molecular Crystals and Liquid Crystals in 2019.COA of Formula: C6H8S The following contents are mentioned in the article:

Photochromic core structure, triangle terthiophene, is configured to the design of 2,3-Bis(2,5-dimethylthiophen)-5-methoxyphenylethynylthiophene (PT) and 2,3-Bis(2,5-dimethylthiophen)-5-(4-methoxyphenyl)-1,3-butadiene-1,1,4,4-tetracarbonitrile(MPT) and characterized by NMR and HRMS technol. The photochromic behavior is investigated in typical solvents. With in hexane, reversibly photochromic process is induced by alternative irradiation of UV and Visible light. The solution color of can be toggled between colorless and pink, forming a switch cycle. In chloroform, the photochromic wavelength moves to shorter wavelength side. For, UV light induced photochromism is not observed Due to the addition of tetracarbonitrile, its strong electron-withdrawing character significantly lowers the electron d. on reactive carbon atoms in LUMO, which is one of the key elements to support the photoactive of photochromism. Therefore, the mol. configuration of electron distribution is important to the design of photochromic dyes. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8COA of Formula: C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.COA of Formula: C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Li, Shimeng et al. published their research in Journal of the American Chemical Society in 2022 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Related Products of 638-02-8

Visible-Light-Promoted Nickel-Catalyzed Cross-Coupling of Iodocarboranes with (Hetero)Arenes via Boron-Centered Carboranyl Radicals was written by Li, Shimeng;Xie, Zuowei. And the article was included in Journal of the American Chemical Society in 2022.Related Products of 638-02-8 The following contents are mentioned in the article:

A general strategy for the generation of hypervalent B-centered carboranyl radicals at the B(3), B(4), and B(9) positions was developed for the 1st time via visible-light-promoted I atom abstraction from iodo-o-carboranes by low-valent Ni complex. These radicals react with various (hetero)arenes to afford a wide range of cage B-arylated carborane derivatives at room temperature in very good to excellent yields with a broad substrate scope. Their electrophilicities are dependent on the vertex charges of the cage and follow the order B(3) > B(4) > B(9). Both visible light and Ni catalyst are proved critical to the generation of B-centered carboranyl radicals. The involvement of B radicals is supported by control experiments A reaction mechanism associated with these reactions is also proposed. This strategy offers a new protocol for the generation of B-centered carboranyl radicals at the selected B vertex, leading to a facile synthesis of a large class of cage B substituted carborane mols. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Related Products of 638-02-8).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Related Products of 638-02-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Wang, Aimei et al. published their research in Fungal Biology in 2018 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is also used in the manufacturing of dyes such as thioindigo.Related Products of 638-02-8

Discriminant analysis of volatile organic compounds of Fusarium oxysporum f. sp. cepae and Fusarium proliferatum isolates from onions as indicators of fungal growth was written by Wang, Aimei;Haapalainen, Minna;Latvala, Satu;Edelenbos, Merete;Johansen, Anders. And the article was included in Fungal Biology in 2018.Related Products of 638-02-8 The following contents are mentioned in the article:

Basal rot is a common onion disease and is mainly caused by Fusarium oxysporum f. sp. cepae and Fusarium proliferatum. To study the possibility of using volatile organic compounds (VOCs) as biomarkers for these fungi, pathogenic isolates of F. oxysporum and F. proliferatum from onions were cultivated in onion medium and VOCs were measured by solid phase microextraction (SPME). Forty-two compounds were detected, and thirty of these compounds were highly related to fungal metabolic activity. Allyl mercaptan was specific to F. oxysporum isolate Fox006. Anal. of the VOCs showed significant differences between the two species and among different isolates within the same species. Sixteen of the VOCs showed were highly pos. correlated with the fungal biomass estimated by real-time polymerase chain reaction (PCR). Ethanol, Et formate, Et acetate, 2-methyl-1-propanol, Me thioacetate, Pr acetate and 3-methyl-1-butanol are volatile metabolites that were potential indicators of Fusarium growth on onions. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Related Products of 638-02-8).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is also used in the manufacturing of dyes such as thioindigo.Related Products of 638-02-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Zhou, Rong et al. published their research in Chemical Science in 2017 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Synthetic Route of C6H8S

Metal-free direct alkylation of unfunctionalized allylic/benzylic sp3 C-H bonds via photoredox induced radical cation deprotonation was written by Zhou, Rong;Liu, Haiwang;Tao, Hairong;Yu, Xingjian;Wu, Jie. And the article was included in Chemical Science in 2017.Synthetic Route of C6H8S The following contents are mentioned in the article:

Despite notable recent efforts, a catalytic and convenient strategy for the direct alkylation of unactivated allylic or benzylic C(sp3)-H bonds remains a formidable challenge facing the synthesis community. Herein, an unprecedented allylic/benzylic alkylation using only an organo-photoredox catalyst, which enables coupling of a broad scope of alkenes/arenes and electron-deficient alkenes in an atom- and redox-economic manner has been reported. A photoredox induced alkene/arene radical cation deprotonation is proposed to smoothly generate the key allylic and benzylic radical intermediates. It represents the first C-C bond formation via radical cation deprotonation under visible light conditions. The resulting products can be easily scaled up and directly converted to γ,δ-unsaturated or α,β-diaryl-acids, -esters, -amides, -pyrazoles, -isoxazoles, as well as lactones, which enables this mild and selective sp3 C-H alkylation to rapidly access complex bioactive mols. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Synthetic Route of C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Synthetic Route of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Kumar, N. R. Prasanna et al. published their research in Indian Journal of Agricultural Sciences in 2017 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Recommanded Product: 2,5-Dimethylthiophene

Herbivore induced plant volatiles represents a favorable host to onion thrips (Thrips tabaci) was written by Kumar, N. R. Prasanna;Jayanthi, P. D. Kamala;Kempraj, Vivek;Ravindra, M. A.;Roy, T. K.;Verghese, A.. And the article was included in Indian Journal of Agricultural Sciences in 2017.Recommanded Product: 2,5-Dimethylthiophene The following contents are mentioned in the article:

Onion thrips, Thrips tabacis Lindeman (Thysanoptera: Thripidae) is an important pest of horticulture crops throughout the globe. However, there is a paucity of studies on its behavioral ecol. in relation to herbivore induced plant volatiles (HIPVs). An attempt was made to study behavior of T. tabaci towards HIPVs and healthy plant volatiles. Olfactometer bioassays revealed that T. tabaci significantly preferred HIPVs from conspecific infested onion to volatiles from healthy onion plants. Gas chromatog.-Mass spectrometry (GC-MS) anal. of HIPVs and volatiles from healthy onion plants revealed substantial changes in their volatile profiles. Our study provides empirical data on signals HIPVs may provide herbivores and suggests that the role of HIPVs, mostly generalized as defense, may vary based on the interaction and must be studied closely to understand their ecol. roles. It also provides basis for the development of kairomone based management strategies against this devastating pest. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Recommanded Product: 2,5-Dimethylthiophene).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Recommanded Product: 2,5-Dimethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Gorsline, Bradley J. et al. published their research in Journal of the American Chemical Society in 2017 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is also used in the manufacturing of dyes such as thioindigo.Application of 638-02-8

C-H Alkenylation of Heteroarenes: Mechanism, Rate, and Selectivity Changes Enabled by Thioether Ligands was written by Gorsline, Bradley J.;Wang, Long;Ren, Peng;Carrow, Brad P.. And the article was included in Journal of the American Chemical Society in 2017.Application of 638-02-8 The following contents are mentioned in the article:

Thioether ancillary ligands have been identified that can greatly accelerate the C-H alkenylation of O-, S-, and N-heteroarenes. Kinetic data suggest thioether-Pd-catalyzed reactions can be as much as 800× faster than classic ligandless systems. Furthermore, mechanistic studies revealed C-H bond cleavage as the turnover-limiting step, and that rate acceleration upon thioether coordination is correlated to a change from a neutral to a cationic pathway for this key step. The formation of a cationic, low-coordinate catalytic intermediate in these reactions may also account for unusual catalyst-controlled site selectivity wherein C-H alkenylation of five-atom heteroarenes can occur under electronic control with thioether ligands even when this necessarily involves reaction at a more hindered C-H bond. The thioether effect also enables short reaction times under mild conditions for many O-, S-, and N-heteroarenes (55 examples), including examples of late-stage drug derivatization. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Application of 638-02-8).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is also used in the manufacturing of dyes such as thioindigo.Application of 638-02-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Xie, Bojie et al. published their research in Molecules in 2022 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Electric Literature of C6H8S

Optimization of Headspace Solid-Phase Micro-Extraction Conditions (HS-SPME) and Identification of Major Volatile Aroma-Active Compounds in Chinese Chive (Allium tuberosum Rottler) was written by Xie, Bojie;Wu, Qian;Wei, Shouhui;Li, Haiyan;Wei, Jinmei;Hanif, Medhia;Li, Ju;Liu, Zeci;Xiao, Xuemei;Yu, Jihua. And the article was included in Molecules in 2022.Electric Literature of C6H8S The following contents are mentioned in the article:

In order to rapidly and precisely identify the volatile compounds in Chinese chive (Allium tuberosum Rottler), seven key parameters of headspace solid-phase micro-extraction conditions (HS-SPME) from Chinese chive were optimized. A total of 59 volatile compounds were identified by using the optimized method, including 28 ethers, 15 aldehydes, 6 alcs., 5 ketones, 2 hydrocarbons, 1 ester, and 2 phenols. Ethers are the most abundant, especially di-Me trisulfide (10,623.30μg/kg). By calculating the odor activity values (OAVs), 11 volatile compounds were identified as the major aroma-active compounds of Chinese chive. From the anal. of the composition of Chinese chive aroma, the “garlic and onion” odor (OAV = 2361.09) showed an absolute predominance over the other 5 categories of aroma. The results of this study elucidated the main sources of Chinese chive aroma from a chem. point of view and provided the theor. basis for improving the flavor quality of Chinese chive. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Electric Literature of C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Electric Literature of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Choi, So Mang et al. published their research in Food Chemistry in 2017 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is also used in the manufacturing of dyes such as thioindigo.Reference of 638-02-8

Volatile composition and sensory characteristics of onion powders prepared by convective drying was written by Choi, So Mang;Lee, Dong-Jin;Kim, Jong-Yea;Lim, Seung-Taik. And the article was included in Food Chemistry in 2017.Reference of 638-02-8 The following contents are mentioned in the article:

Volatile composition and sensory characteristics of onion powders prepared by convective drying at different temperatures (50, 70, and 90 °C) were investigated. Di-Pr disulfide was the major volatile compound in fresh onion (77.70% of total volatile compounds). However it was considerably lost during drying, reaching 6.93-32.25 μg/g solids. Di-Pr disulfide showed a pos. correlation with green sensory attribute perceived by descriptive sensory anal. Thiophenes, which were responsible for caramel and sweet attributes, were produced by drying especially when the drying temperature was high. Aldehydes, another type of volatile compound found in fresh onion, showed a pos. correlation with humidity. The aldehyde content in dried onion was the highest at the lowest drying temperature, possibly because the aldehydes were produced by the residual enzymes in fresh onion. Using a low temperature for drying was ideal to retain the aroma of fresh onion. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Reference of 638-02-8).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is also used in the manufacturing of dyes such as thioindigo.Reference of 638-02-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Zhang, Shaofei et al. published their research in Chem in 2021 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Recommanded Product: 638-02-8

Unlocking the Friedel-Crafts arylation of primary aliphatic alcohols and epoxides driven by hexafluoroisopropanol was written by Zhang, Shaofei;Vayer, Marie;Noel, Florent;Vukovic, Vuk D.;Golushko, Andrei;Rezajooei, Nazanin;Rowley, Christopher N.;Leboeuf, David;Moran, Joseph. And the article was included in Chem in 2021.Recommanded Product: 638-02-8 The following contents are mentioned in the article:

The limitations thar easily overcome using Bronsted acid catalysis in hexafluoroisopropanol (HFIP) as a solvent were reported. Electron-poor aromatic epoxides and aliphatic epoxides undergo stereospecific arylation to give alcs. RC(R1)(Ar)CH2OH/RCH(OH)CH(Ar)OH, and based on the reaction conditions, it can partake in a second nucleophilic substitution with a different arene ArH in one pot. Ph ethanols R3(CH2)2OH (R3 = Ph, 2,6-dichlorophenyl, 2,4,6-trimethylphenyl, etc.) react through a phenonium intermediate, whereas simple aliphatic alcs. e.g., cyclopentanol participate in a rare intermol. SN2 Friedel-Crafts process, delivering linear products e.g., 1,3,5-trimethyl-2-phenethylbenzene exclusively. In this work, an alternative to metal-catalyzed cross-couplings was provided for accessing important scaffolds, and widening the range of applications of the Friedel-Crafts reaction. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Recommanded Product: 638-02-8).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Recommanded Product: 638-02-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Aqlan, Faisal M. et al. published their research in Polycyclic Aromatic Compounds in 2022 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Reference of 638-02-8

Synthesis Characterization and In Vitro Antibacterial Activity of the N-Substituted Bis-Pyrazoline Derivative as Polycyclic Aromatic Compounds was written by Aqlan, Faisal M.. And the article was included in Polycyclic Aromatic Compounds in 2022.Reference of 638-02-8 The following contents are mentioned in the article:

N-substituted bis-pyrazolines I [R = 4-MeC6H4NH, 2-ClC6H4NH, 4-O2NC6H4NH, 2,4-F2C6H3NH, 2,6-F2C6H3NH] were synthesized by the reaction of bis-chalcone with N-substituted thiosemicarbazide derivatives under basic conditions. The bis-chalcone was synthesized by the reaction of 1-(2,5-dimethylthiophen-3-yl)ethan-1-one with terephthalaldehyde under basic condition. The in vitro antibacterial activity of I was estimated against two Gram-pos. and two Gram-neg. bacterial strains by the disk diffusion method and min. inhibitory concentration (MIC) method and the results were compared with standard drug Amoxicillin. The structure-activity relationship showed that I (R = 2-ClC6H4NH) was more active than standard drug Amoxicillin. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Reference of 638-02-8).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Reference of 638-02-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem