Category: 638-02-8

Chiral acid-catalysed enantioselective C-H functionalization of toluene and its derivatives driven by visible light was written by Li, Fuyuan;Tian, Dong;Fan, Yifan;Lee, Richmond;Lu, Gang;Yin, Yanli;Qiao, Baokun;Zhao, Xiaowei;Xiao, Ziwei;Jiang, Zhiyong. And the article was included in Nature Communications in 2019.Category: benzothiophene The following contents are mentioned in the article:

Here, photoinduced radical-based enantioselective C(sp³)-C(sp³) coupling reactions of activated ketones with toluene and its derivatives by means of chiral acid catalysis was reported. With a La(OTf)₃/pybox complex catalyst, a variety of chiral 3-hydroxy-3-benzyl-substituted 2-oxindoles, including many conventionally difficult-to-access variants, are obtained directly from isatins in high yields with good to excellent enantioselectivities. Acenaphthoquinone is also compatible with the use of a chiral phosphoric acid (CPA) catalyst, leading to another series of important enantioenriched tertiary alcs. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Category: benzothiophene).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Category: benzothiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Homolytic Aromatic Sulfonation with K₂S₂O₅ Promoted by a Combination of Mn(OAc)₃·2H₂O and HFIP was written by Han, Bingxu;Gu, Xin;Li, Ke;Qi, Yunkun;Liang, Shuai. And the article was included in Journal of Organic Chemistry in 2022.SDS of cas: 638-02-8 The following contents are mentioned in the article:

Herein, authors reported a so far unprecedented Mn(OAc)₃·2H₂O-promoted homolytic aromatic sulfonation. The reaction was performed under mild conditions with K₂S₂O₅ employed as a green sulfonating reagent. Various arenes were successfully converted into desired sulfonic acids or sulfonates in high efficiency. Preliminary mechanistic studies demonstrated that the present reaction proceeds via a homolytic aromatic substitution-type mechanism involving an SO₃^– radical. The combination of Mn(OAc)₃·2H₂O and HFIP plays a crucial role. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8SDS of cas: 638-02-8).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is also used in the manufacturing of dyes such as thioindigo.SDS of cas: 638-02-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Regioselective Arene and Heteroarene Functionalization: N-Alkenoxypyridinium Salts as Electrophilic Alkylating Agents for the Synthesis of α-Aryl/α-Heteroaryl Ketones was written by Zhai, Rong L.;Xue, Yun S.;Liang, Ting;Mi, Jia J.;Xu, Zhou. And the article was included in Journal of Organic Chemistry in 2018.SDS of cas: 638-02-8 The following contents are mentioned in the article:

Gold-catalyzed regioselective Friedel-Crafts reactions of terminal alkynes with arenes and heteroarenes mediated an N-hydroxypyridinium salt (generated in situ from pyridine-N-oxide and triflimide) yielded 1-(hetero)aryl-2-alkanones. The Friedel-Crafts reactions occurred via alkenyloxypyridinium salts formed in situ from an N-hydroxypyridinium salt and the terminal alkynes. The mechanism of the reaction was studied using DFT calculations, isolation and reaction of a methylenedecyloxypyridinium salt, and determination of the deuterium kinetic isotope effect in Friedel-Crafts reactions with benzene and hexadeuterobenzene. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8SDS of cas: 638-02-8).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.SDS of cas: 638-02-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Tris-NHC-propagated self-supported polymer-based Pd catalysts for heterogeneous C-H functionalization was written by Mandal, Tanmoy;Dutta, Tapas Kumar;Mohanty, Sunit;Choudhury, Joyanta. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2021.COA of Formula: C6H8S The following contents are mentioned in the article:

Three-dimensionally propagated imidazolium-containing mesoporous coordination polymer and organic polymer-based platforms were successfully exploited to develop single-site heterogenized Pd-NHC catalysts for oxidative arene/heteroarene C-H functionalization reactions. The catalysts were efficient in directed arene halogenation, and nondirected arene and heteroarene arylation reactions. High catalytic activity, excellent heterogeneity and recyclability were offered by these systems making them promising candidates in the area of heterogeneous C-H functionalization, where efficient catalysts are still scarce. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8COA of Formula: C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is also used in the manufacturing of dyes such as thioindigo.COA of Formula: C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Direct alkylation of thiophenes via bis-coupling with vinyl acetates was written by Zhang, Tong;Wang, Nai-Xing;Wu, Yue-Hua;Yan, Zhan;Xing, Yalan;Wen, Jia-Long;Gao, Xue-Wang. And the article was included in Tetrahedron Letters in 2018.Recommanded Product: 2,5-Dimethylthiophene The following contents are mentioned in the article:

A novel direct alkylation of thiophenes via bis-coupling with vinyl acetates has been developed. To the best of our knowledge, this represents the first report of the iron-catalyzed coupling of two thiophenes with vinyl groups. Utilizing earth-abundant, inexpensive, and non-toxic iron catalysts, this methodol. converts simple thiophenes to sym. dithienylethane derivatives I (R¹ = 5-Et, 5-Me, 5-Cl, etc.; R² = H, Me, (CH₂)₂COOH; R³ = H; R² = R³ = -(CH₂)₅-) under mild conditions in one step. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Recommanded Product: 2,5-Dimethylthiophene).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Recommanded Product: 2,5-Dimethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Geographical discrimination and authentication of Chinese garlic based on multi-element, volatile and metabolomics profiling combined with chemometrics was written by Mi, Si;Zhang, Xiangnan;Wang, Yuhang;Yan, Fulong;Sang, Yaxin;Gong, Heyou;Wang, Xianghong. And the article was included in Food Control in 2021.Synthetic Route of C6H8S The following contents are mentioned in the article:

This study aims to discriminate the garlics collected from four different geog. locations of China. The multi-element (12 samples), volatile (12 samples) and metabolome (24 samples) composition of the garlics were analyzed and compared. A total of 34 chem. elements, 68 volatiles and 854 metabolites were detected in the garlic samples. Significant differences were observed in the chem. element, volatile and metabolomics profiles of the four groups of garlic. Multivariate statistics indicate that 10 chem. elements, 6 volatiles and 225 metabolites could be used as candidate markers for the separation of garlics obtained from Langfang, Jining, Kaifeng and Dali of China. The current work provides a chem. fingerprint of the selected Chinese garlics. Our results demonstrate that chem. profiling in combination with chemometrics has the potential to be used as feasible approaches for the authentication of the geog. origin of garlic. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Synthetic Route of C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is also used in the manufacturing of dyes such as thioindigo.Synthetic Route of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Identification of bioactive compounds of pyrolysis oil obtained from cotton residues (Gossypium arboreum) by flash pyrolysis was written by Madhu, P.;Periyanayagi, G.. And the article was included in International Journal of ChemTech Research in 2017.Computed Properties of C6H8S The following contents are mentioned in the article:

Pyrolysis oils have attracted a lot of interest, as they are liquid energy carriers and general sources of chems. In this work the gas chromatog.-mass spectroscopy was developed and applied for the anal. of bioactive and hydrocarbons of pyrolysis bio oil. More than 250 bioactive compounds such as normal saturated hydrocarbons, cyclopentane, cyclohexane, esters, alcs., sulfur- and bromo-containing compounds, simple pyrane, and benzene derivatives, were identified. Most of these compounds have not been reported earlier. The increase in the number of identified products is due to increased separations This increased understanding of pyrolytic product distribution can be used to enhance our understanding of the formation mechanisms of pyrolytic products. The method described in this article is a suitable research tool for the determination of various chem. compounds from pyrolysis bio oil derives from cotton shell. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Computed Properties of C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Computed Properties of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Photochemical Intramolecular C-H Addition of Dimesityl(hetero)arylboranes by a [1,6]-Sigmatropic Rearrangement was written by Ando, Naoki;Fukazawa, Aiko;Kushida, Tomokatsu;Shiota, Yoshihito;Itoyama, Shuhei;Yoshizawa, Kazunari;Matsui, Yasunori;Kuramoto, Yutaro;Ikeda, Hiroshi;Yamaguchi, Shigehiro. And the article was included in Angewandte Chemie, International Edition in 2017.Synthetic Route of C6H8S The following contents are mentioned in the article:

A new reaction mode for triarylboranes under photochem. conditions was discovered. Photoirradiation of dimesitylboryl-substituted (hetero)arenes produced spirocyclic boraindanes, where one of the C-H bonds in the ortho-Me groups of the mesityl substituents was formally added in a syn fashion to a C-C double bond of the (hetero)aryl group. Quantum chem. calculations and laser flash photolysis measurements indicated that the reaction proceeds by a [1,6]-sigmatropic rearrangement. This behavior is reminiscent of the photochem. reaction mode of arylalkenylketones, thus demonstrating the isosteric relation between tricoordinate organoboron compounds and the corresponding pseudo-carbocationic species in terms of pericyclic reactions. Despite the disrupted π-conjugation, the resulting spirocyclic boraindanes exhibited a characteristic absorption band at relatively long wavelengths (λ=370-400 nm). This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Synthetic Route of C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is also used in the manufacturing of dyes such as thioindigo.Synthetic Route of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Formation of S-alkyl thiophenium ionic liquids: mechanistic rationale and structural relationships was written by Schiel, Maria A.;Garcia de la Concepcion, Juan;Domini, Claudia E.;Cintas, Pedro;Silbestri, Gustavo F.. And the article was included in Organic & Biomolecular Chemistry in 2019.Synthetic Route of C6H8S The following contents are mentioned in the article:

The quaternization of thiophenes through S-alkylation reactions with iodoalkanes in the presence of silver salts opens the door to a new family of room-temperature ionic liquids, yet relatively unexplored in terms of chem. reactivity and applications. This computational study provides a mechanistic rationale that accounts for their formation. The results are consistent with the calculated energy barriers of the corresponding transition structures. Calculations indicate that the geometry at the sulfur atom goes from flat to tetrahedral during salt formation, and the electron delocalization of thiophene is greatly reduced, if not lost, as inferred from aromaticity indexes. Moreover, the rationale explains the influence of polarizable anions on S-alkylation and why alkyl substitution at the α-position of thiophenes gives rise to more stable species than unsubstituted derivatives This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Synthetic Route of C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Synthetic Route of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Hydrothermal conversion of biomass (Xanthium strumarium) to energetic materials and comparison with other thermochemical methods was written by Durak, Halil;Genel, Yasar. And the article was included in Journal of Supercritical Fluids in 2018.Category: benzothiophene The following contents are mentioned in the article:

In the present study, the biomass was converted into liquid and solid residues by using hydrothermal liquefaction method at 250, 300 and 350°C with (FeCl₃, NaOH) and without catalyst. The resultant products were examined using GC-MS, FT-IR, ¹H NMR, SEM, and elemental anal. methods. According to the performed analyses, the highest liquid product yield (total bio-oil) was found to be 38.08% at 300°C by using FeCl₃ as catalyst. In the experiments carried out at 350°C, the highest HHV value was found to be 32.35 MJ kg^-1 by using NaOH catalyst. The energy values of products obtained at the end of experiments were compared to the values obtained from pyrolysis and supercritical liquefaction method, and it was determined that the liquid products having higher level of energy value were achieved by using hydrothermal liquefaction method. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Category: benzothiophene).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Category: benzothiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem