Analyzing the synthesis route of 6179-28-8

6179-28-8 Benzo[b]thiophen-6-ylmethanol 13540121, abenzothiophene compound, is more and more widely used in various fields.

6179-28-8, Benzo[b]thiophen-6-ylmethanol is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of compound B-201 (2.0 g, 12 mmol) and manganese dioxide (1 1 g, 0.12 mol) in dichloromethane (40 mL) was stirred at room temperature for 12 hours. On completion, the mixture was filtered, and the resulting filtrate was concentrated in vacuo to give crude compound B-202 (1.5 g, 76% yield) as a colorless oil. LCMS: (ES+) m/z (M+H)+ – 163.2, tR= 0.721 ., 6179-28-8

6179-28-8 Benzo[b]thiophen-6-ylmethanol 13540121, abenzothiophene compound, is more and more widely used in various fields.

Reference£º
Patent; FORUM PHARMACEUTICALS, INC.; BURNETT, Duane, A.; BURSAVICH, Matthew, Gregory; MCRINER, Andrew, J.; WO2015/66371; (2015); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem

 

Some tips on 6179-28-8

As the paragraph descriping shows that 6179-28-8 is playing an increasingly important role.

6179-28-8,6179-28-8, Benzo[b]thiophen-6-ylmethanol is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Phosphorus oxybromide (2.7 g) was added to a solution of 6-hydroxymethylbenzo[b]thiophene (0.7 g) in ether (50 ml) at reflux. After 3 h at reflux the solution was washed with water, aqueous sodium hydrogen carbonate, and brine, dried (MgSO4) and evaporated to give the title compound (0.7 g).

As the paragraph descriping shows that 6179-28-8 is playing an increasingly important role.

Reference£º
Patent; Bruton, Gordon; Faller, Andrew; Orlek, Barry Sidney; Rana, Kishore Kalidas; Walker, Graham; US2003/199571; (2003); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem