Awesome Chemistry Experiments For Methyl 3-aminobenzo[b]thiophene-2-carboxylate

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BENZOFURO- AND BENZOTHIENOPYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR

Benzofuro-and benzothienopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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Synthesis and Reactions of 2H-Benzothieno<3,2-d><1,3>oxazine-2,4(1H)-dione

The title compound 5 is synthesized by the reaction of the potassium salt of 3-aminobenzothiophene-2-carboxylic acid with phosgene.Compound 5 is readily alkylated to give 6 with methyl iodide, benzyl bromide, or propargyl bromide in the presence of sodium hydride.Reaction of 5 and 6 with nucleophiles follows specifically different pathways.Compound 5 is readily ionized to the isocyanate species 13 and subsequently reacts with methanol or methylamine to produce exclusively the carbamate 7 or ureido acid 9.The N-substituted derivative 6, in analogous reaction withmethanol or methylamine, produce exclusively the amino ester 8 or the amino amide 10.The N-benzyl derivative 6b reacts with the cyclic S-methylthiopseudourea 11 to give the tetracycle 12, a new ring system.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 35212-85-2. In my other articles, you can also check out more blogs about 35212-85-2

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Tricyclic aminopyrimidine histamine H4 receptor antagonists

This report discloses the development of a series of tricyclic histamine H4 receptor antagonists. Starting with a low nanomolar benzofuranopyrimidine HTS hit devoid of pharmaceutically acceptable properties, we navigated issues with metabolism and solubility to furnish a potent, stable and water soluble tricyclic histamine H4 receptor antagonist with desirable physiochemical parameters which demonstrated efficacy a mouse ova model.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 35212-85-2 is helpful to your research. Reference of 35212-85-2

Reference of 35212-85-2, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 35212-85-2, molcular formula is C10H9NO2S, introducing its new discovery.

ORGANIC COMPOUND AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE

For an organic compound represented by formula 1, organic optoelectronic device and the display device are disclosed. [Formula 1] In said formula 1, Ar1 , Ar2 , L1 , L2 , R1 To R3 Efined specification is based on. (by machine translation)

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Archives for Chemistry Experiments of Methyl 3-aminobenzo[b]thiophene-2-carboxylate

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Novel hetero-cyclic compound and organic light emitting device comprising the same

The present invention refers to novel heterocyclic compounds and organic light emitting device using the same number […] substrate. (by machine translation)

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor

The present paper describes the synthesis and the binding properties for the serotonergic 5-HT7 and 5-HT1A receptors of three new series (A?C) of (benzo)thienopyrimidinone derivatives. All series exhibit a basic moiety at the 2-position of the heterocyclic scaffold such as N,N-dialkylaminoalkylthio chain in series A and phenylpiperazine, benzylpiperazine, or benzylpiperidine alkyl chain in series B and C. Compounds endowed with the best binding properties at 5-HT7R belong to the B and C types. In particular, derivatives B2 and C1 (RSC4) exhibit notable affinity for 5-HT7R (Ki = 9.08 and 0.85 nM, respectively) and selectivity over the 5-HT1AR (254- and 48-fold, respectively). The structure-affinity relationships for these three new classes of 5-HT7R ligands are discussed and, in order to rationalize and deeply investigate the observed results, molecular modeling studies were performed. In particular, the binding poses of the synthesized compounds were studied by docking them in the two receptor proteins suitably built by homology modeling. The calculated binding energies resulted in an excellent agreement with the experimental measured Ki, further validating the quality of the models.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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FUSED CYCLIC MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION

Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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FUSED CYCLIC MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION

Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.

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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 35212-85-2, and how the biochemistry of the body works.Application of 35212-85-2

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METHOD FOR PROMOTING PLANT GROWTH

The present invention provides a method for promoting plant growth, which comprises treating a plant with a compound represented by the following Formula (1): provided that a method for promoting plant growth which comprises treating plants with a compound corresponding to any one of the following (1) to (8) is excluded: (1) Methyl 4-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (2) Methyl 5-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (3) Methyl 6-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (4) Methyl 7-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (5) Ethyl 4-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (6) Ethyl 5-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, (7) Ethyl 6-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, and (8) Ethyl 7-(trifluoromethyl)benzo[b]thiophene-2-carboxylate.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 35212-85-2, and how the biochemistry of the body works.Application of 35212-85-2

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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MODULATORS OF CCR9 RECEPTOR AND METHODS OF USE THEREOF

Provided are compounds that are modulators of CCR9 receptor activity, compositions containing the compounds and methods of use of the compounds and compositions. In certain embodiments, provided are methods for treating or ameliorating diseases associated with modulation of CCR9 receptor activity.

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Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem