Category: 22720-75-8

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.22720-75-8,2-Acetylbenzothiophene,as a common compound, the synthetic route is as follows.

To a solution of compound 1 (1.76 g, 12 mmol) and compound 2 (1.76 g, 10 mmol) dissolved in ethanol (20 ml) was added an aqueous solution of potassium hydroxide (1.12 g, 20 mmol) (1.1 ml). The mixture was stirred at room temperature overnight, and water was added to the mixture and precipitates were collected by filtration. The pre- cipitates were washed with water, dissolved in ethyl acetate-THF, and dried over anhydrous magnesium sulfate. Activated charcoal was added to the extract, and the mixture was filtered and the filtrate was concentrated. The residue was triturated from ethyl acetate-isopropyl ether to give compound 3 (2.36 g, [77 percent).] MS-APCI (m/z): 305/307 [([M+H] +)]

22720-75-8, 22720-75-8 2-Acetylbenzothiophene 89805, abenzothiophene compound, is more and more widely used in various fields.

Reference£º
Patent; Tanabe Seiyaku Co., Ltd.; WO2004/35570; (2004); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem

22720-75-8, 2-Acetylbenzothiophene is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A solution of l-(benzo[b]thiophen-2-yl)ethanone (1 g) in dimethoxy-N,N-dimethyl- methanamine (10 mL) was refluxed for 6 h and then cooled to rt. The precipitate was filtered and washed with diethyl ether to afford the title compound (l.lg, 84percent).

22720-75-8, As the paragraph descriping shows that 22720-75-8 is playing an increasingly important role.

Reference£º
Patent; AMGEN, INC.; WO2006/66172; (2006); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem