Category: 1795-01-3

Rapid Syntheses of Oligo(2,5-thiopheneethynylene)s with Thioester Termini: Potential Molecular Scale Wires with Alligator Clips was written by Pearson, Darren L.;Tour, James M.. And the article was included in Journal of Organic Chemistry in 1997.Computed Properties of C6H8S This article mentions the following:

The syntheses of soluble oligo(3-ethyl-2,5-thiopheneethynylene)s via an iterative divergent/convergent approach starting from 3-ethyl-2-[(trimethylsilyl)ethynyl]thiophene are described. The monomer, dimer, tetramer, octamer, and 16-mer were synthesized. The 16-mer is 100 Å long in its minimized extended zigzag conformation. At each stage in the iteration, the length of the framework doubles. Only three sets of reaction conditions are needed for the entire iterative synthetic sequence: an iodination, a protodesilylation, and a Pd/Cu-catalyzed cross-coupling. The oligomers were characterized spectroscopically and by mass spectrometry. The optical properties show that at the octamer stage, the optical absorbance maximum is nearly saturated The size exclusion chromatog. values for the number average weights, relative to polystyrene, illustrate the tremendous differences in the hydrodynamic volume of these rigid rod oligomers vs. the random coils of polystyrene. These differences become quite apparent at the octamer stage. Attachment of thiol end groups, protected as the thioacetyl moieties, was achieved. These serve as binding sites for adhesion to gold surfaces. In some cases, one end of the oligomeric chains was capped with a thiol group so that the surface attachments to gold could be studied. In other cases, thiol groups were affixed to both ends of the mol. chains so that future conduction studies could be done between proximal metallic probes. The rigid rod conjugated oligomers may act as mol. wires in mol. scale electronic devices, and they also serve as useful models for understanding analogous bulk polymers. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Computed Properties of C6H8S).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Computed Properties of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Asymmetric benzylic C(sp³)-H acylation via dual nickel and photoredox catalysis was written by Huan, Leitao;Shu, Xiaomin;Zu, Weisai;Zhong, De;Huo, Haohua. And the article was included in Nature Communications in 2021.HPLC of Formula: 1795-01-3 This article mentions the following:

An asym. benzylic C-H acylation of alkylarenes employing carboxylic acids as acyl surrogates for synthesis of α-aryl ketones I [R¹ = Me, 2-thienyl, 2-naphthyl, etc.; R² = Me, Et, CH₂CH₂OAc, etc.; Ar = 3-thienyl, 4-FC₆H₄, 1,1′-biphenyl, etc.] via nickel and photoredox dual catalysis was reported. This mild yet straightforward protocol transformed a diverse array of feedstock carboxylic acids and simple alkyl benzenes into highly valuable α-aryl ketones with high enantioselectivities. The utility of this method was showcased in gram-scale synthesis and late-stage modification of medicinally relevant mols. Mechanistic studies suggested a photocatalytically generated bromine radical could perform benzylic C-H cleavage to activate alkylarenes as nucleophilic coupling partners which could then engage in a nickel-catalyzed asym. acyl cross-coupling reaction. This bromine-radical-mediated C-H activation strategy could be also applied to enantioselective coupling of alkylarenes with chloroformate for synthesis of chiral α-aryl esters, e.g., II. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3HPLC of Formula: 1795-01-3).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.HPLC of Formula: 1795-01-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Visible-Light-Induced [4+2] Annulation of Thiophenes and Alkynes to Construct Benzene Rings was written by Song, Chunlan;Dong, Xin;Wang, Zhongjie;Liu, Kun;Chiang, Chien-Wei;Lei, Aiwen. And the article was included in Angewandte Chemie, International Edition in 2019.Reference of 1795-01-3 This article mentions the following:

Herein, an efficient strategy was developed for visible-light induced photocatalyzed [4+2] annulation of thiophenes and alkynes to afford substituted aromatic compounds Valuable drugs and amino acids were also well tolerated. Moreover, DFT calculations explained the high regioselectivity of the reaction. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Reference of 1795-01-3).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Reference of 1795-01-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Pyrolytic chemistry of thenyl benzoates was written by Chen, Ping-Shu;Chou, Chin-Hsing. And the article was included in Tetrahedron in 1996.Safety of 3-Ethylthiophene This article mentions the following:

Flash vacuum pyrolysis of 2- and 3-thenyl benzoates at temperatures in the range 550-750° and ca. 10^-2 torr gave several radical-derived products. The mechanism of formation of these pyrolysis products is proposed to involve 2- and 3-thenyl and Ph radicals. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Safety of 3-Ethylthiophene).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is also used in the manufacturing of dyes such as thioindigo.Safety of 3-Ethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

A Study on FCC gasoline hydro-upgrading was written by Yang, Xiaoyu;Yuan, Jingli;Wang, Xiangsheng;Guo, Xinwen. And the article was included in Zhongwai Nengyuan in 2012.Application of 1795-01-3 This article mentions the following:

Producing clean gasoline with low sulfur and olefin contents and high octane number is required by the need for achieving sustainable growth of energy economy. China began implementing the Limits and Measurement of Pollutants Emitted by Light Vehicles (China Phase IV) in 2011 nationwide. According to the standard, the volume fraction of olefin in gasoline should not exceed 18%, that of aromatic hydrocarbon not exceed 35%, and the content of sulfur not exceed 50μg/g. Around 80% of gasoline products in China come from FCC gasoline and the sulfur content of FCC gasoline accounts for some 90% of sulfur in gasoline. FCC gasoline contains high contents of olefin (mass fraction : 30%-55%) and sulfur (150-1500μg/g). Sulfur in FCC gasoline primarily exists in the forms of thiophene and thiophene derivatives The article analyzes the contribution of hydrocarbon composition in FCC gasoline fractions to octane value and distribution of sulfide and conducts a preliminary forecast of the possibility and results of reactions such as hydrogen transfer, isomerization and aromatic hydrocarbon generation from a thermodn. perspective. The article suggests retaining more high octane-value olefin components while ensuring deep desulfurization and highly selectively converting olefin to aromatic hydrocarbon to maintain the octane value of gasoline products produced. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Application of 1795-01-3).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Application of 1795-01-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Influence of ethylenediamine tetraacetic acid on the hydrodesulfurization activity of nano HZSM-5 supported NiMo catalyst was written by Jin, Feng-Ying;Guo, Xin-Wen;Wang, Xiang-Sheng. And the article was included in Gaodeng Xuexiao Huaxue Xuebao in 2011.Product Details of 1795-01-3 This article mentions the following:

A new type of EDTA-NiMo/nano-HZSM-5 (EDTA = ethylene-diaminetetraacetic acid) catalyst for FCC gasoline hydrodesulfurization was prepared and characterized by XRD, ICP, FTIR, ²⁷Al MAS NMR, TG-DTA, Py-IR, and NH₃-TPD. The catalyst showed higher and more stable hydrodesulfurization (HDS) activity for FCC gasoline than the NiMo/nano-HZM-5 catalyst. The results indicated that there was a strong interaction between EDTA and nano-HZSM-5, which weakened the interaction between the active metal components and support, improved dispersion of active metal components on the support surface. Besides, it was the interaction between EDTA and Ni that promoted the reduction and sulfidation of catalyst. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Product Details of 1795-01-3).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Product Details of 1795-01-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Evaluation of on-line pyrolysis two-dimensional gas chromatography time-of-flight mass spectrometry (Py-GC × GC-ToFMS) on whole sediments from a Mediterranean sapropel sequence was written by Payeur, Amy L.;Meyers, Philip A.;Sacks, Richard D.. And the article was included in Organic Geochemistry in 2011.Quality Control of 3-Ethylthiophene This article mentions the following:

Anal. of the mol. composition of the organic matter (OM) from whole sediment samples can avoid anal. bias that might result from isolation of components from the sediment matrix, but has its own anal. challenges. We evaluated the use of GC × GC-ToFMS to analyze the pyrolysis products of six whole sediment samples obtained from above, within and below a 1 million year old OM-rich Mediterranean sapropel layer. We found differences in pyrolysis products <n-C₂₂ between the OM-rich sapropel samples and the OM-poor background marls. The presence of alkyl pyrroles, probably derived from chlorophyll, in pyrolyzates of the sapropels but not in those of the marls suggests that higher marine productivity and greater OM preservation accompanied deposition of the sapropels. Detection of tetra-Me benzenes considered to be pyrolysis products of isorenieratene in the sapropel samples is evidence that nitrogen-fixing green sulfur bacteria contributed to the high productivity. Greater abundances of shorter chain aliphatic hydrocarbons, pyrroles, furans and alkyl aromatics in the pyrolyzates of sapropel samples relative to the marls confirm better preservation of marine OM in the sapropels. In addition, the presence of greater amounts of thiophenes in the sapropels than in the marls is consistent with the existence of euxinic conditions during sapropel deposition. The combination of whole sediment pyrolysis and GC × GC-ToFMS is promising, but the procedure requires careful selection of its multiple anal. variables, particularly the pyrolysis temperature and the operational features of the GC columns. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Quality Control of 3-Ethylthiophene).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Quality Control of 3-Ethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Multidimensional gas chromatography in combination with accurate mass, tandem mass spectrometry, and element-specific detection for identification of sulfur compounds in tobacco smoke was written by Ochiai, Nobuo;Mitsui, Kazuhisa;Sasamoto, Kikuo;Yoshimura, Yuta;David, Frank;Sandra, Pat. And the article was included in Journal of Chromatography A in 2014.Recommanded Product: 1795-01-3 This article mentions the following:

A method is developed for identification of sulfur compounds in tobacco smoke extract The method is based on large volume injection (LVI) of 10 μL of tobacco smoke extract followed by selectable one-dimensional (¹D) or two-dimensional (²D) gas chromatog. (GC) coupled to a hybrid quadrupole time-of-flight mass spectrometer (Q-TOF-MS) using electron ionization (EI) and pos. chem. ionization (PCI), with parallel sulfur chemiluminescence detection (SCD). In order to identify each individual sulfur compound, sequential heart-cuts of 28 sulfur fractions from ¹D GC to ²D GC were performed with the three MS detection modes (SCD/EI-TOF-MS, SCD/PCI-TOF-MS, and SCD/PCI-Q-TOF-MS). Thirty sulfur compounds were pos. identified by MS library search, linear retention indexes (LRI), mol. mass determination using PCI accurate mass spectra, formula calculation using EI and PCI accurate mass spectra, and structure elucidation using collision activated dissociation (CAD) of the protonated mol. Addnl., 11 mol. formulas were obtained for unknown sulfur compounds The determined values of the identified and unknown sulfur compounds were in the range of 10-740 ng mg total particulate matter (TPM) (RSD: 1.2-12%, n = 3). In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Recommanded Product: 1795-01-3).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Recommanded Product: 1795-01-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Determination of thermal decomposition products of glucose by thermal analysis combined with FTIR and GC-MS was written by Liu, Chun-bo;Shen, Qin-peng;Yang, Guang-yu;Si, Xiao-xi;He, Pei;Wang, Kun-miao;Zhang, Hong-yu;Liu, Zhi-hua;Miao, Ming-ming. And the article was included in Lihua Jianyan, Huaxue Fence in 2014.SDS of cas: 1795-01-3 This article mentions the following:

A combination of thermal anal., FTIR and GC-MS was applied to the determination of thermal decomposition products of glucose. Under conditions of simultaneous thermal anal., the glucose sample was pyrolyzed in atm. of nitrogen and nitrogen oxygen gas mixture, and determined by IR scanning. GC-MS temperature was chosen with thermogravimetric curves and IR spectra. Products of pyrolysis were separated and identified by GC-MS. The exptl. results showed that, 44 compounds were detected in the thermal decomposition products of glucose at temperature of 220°C, 300°C, 350°C and 470°C; 76 compounds were detected in pyrolysis products of glucose at high temperature The anal. results were valuable for the application of glucose at different temperatures In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3SDS of cas: 1795-01-3).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.SDS of cas: 1795-01-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: SAR and Structural Characterization was written by Whelligan, Daniel K.;Solanki, Savade;Taylor, Dawn;Thomson, Douglas W.;Cheung, Kwai-Ming J.;Boxall, Kathy;Mas-Droux, Corine;Barillari, Caterina;Burns, Samantha;Grummitt, Charles G.;Collins, Ian;van Montfort, Rob L. M.;Aherne, G. Wynne;Bayliss, Richard;Hoelder, Swen. And the article was included in Journal of Medicinal Chemistry in 2010.Formula: C6H8S This article mentions the following:

We report herein the first systematic exploration of inhibitors of the mitotic kinase Nek2. Starting from HTS hit aminopyrazine I, compounds with improved activity were identified using structure-based design. Our structural biol. investigations reveal two notable observations. First, I and related compounds bind to an unusual, inactive conformation of the kinase which to the best of our knowledge has not been reported for other types of kinase inhibitors. Second, a phenylalanine residue at the center of the ATP pocket strongly affects the ability of the inhibitor to bind to the protein. The implications of these observations are discussed, and the work described here defines key features for potent and selective Nek2 inhibition, which will aid the identification of more advanced inhibitors of Nek2. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Formula: C6H8S).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Formula: C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem