Category: 17402-83-4

Synthetic Route of 17402-83-4, Chemical Research Letters, May 2021. The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. In a article, 17402-83-4, molcular formula is C8H7NS, introducing its new discovery.

The present invention relates to Brexpiprazole having a purity of about 99.5% or more by area percentage of HPLC, having total impurities not more than 0.5% relative to brexpiprazole as measured by area percentage of HPLC, and having less than 0.1% 1-(benzo[b]thiophen-4-yl)piperazine or a salt thereof relative to brexpiprazole by area percentage of HPLC. The present invention also provides a composition comprising brexpiprazole having 1-(benzo[b]thiophen-4-yl)-piperazine or a salt thereof in an amount less than about 0.1% relative to brexpiprazole by area percentage of HPLC and process for the preparation of brexpiprazole.

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Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

New Advances in Chemical Research in 2021. Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis, new energy materials, preparation and modification of special coatings. Computed Properties of C8H7NS. Introducing a new discovery about 17402-83-4, Name is Benzo[b]thiophen-4-amine

The invention discloses a kind of type (1) a compound represented by the method for preparing brexpiprazole, particularly in 4–aminobenzene and [b] thiophene as the starting material for synthesizing ethylene, to avoid heavy metal palladium-catalyzed reaction, synthesis step and impurities is reduced, reducing the cost of the preparation method. (by machine translation)

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Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Reference of 17402-83-4, Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis, preparation and modification of special coatings, and research on the structure and performance of functional materials. In a article, 17402-83-4, molcular formula is C8H7NS, introducing its new discovery.

The invention provides a piripiprazole derivative and a preparation method, wherein the chemical structural formula of the epiprazole derivative is expressed by a chemical structural formula. The epiprazole derivative is composed of epiconazole, (HCHO). m N – hydroxymethyl according to the first basic catalyst is prepared; and then N – hydroxymethyl-piripiprazole and an alkylformylchloride compound are reacted under second basic catalyst to prepare. The half-life of the epiprazole derivative is prolonged, the drug delivery frequency can be reduced; and the epiprazole derivative prepared by the preparation method is low in impurity, and low in cost. (by machine translation)

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 17402-83-4 is helpful to your research. Reference of 17402-83-4

Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Chemical Research Letters, May 2021. Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction.17402-83-4, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 17402-83-4, Name is Benzo[b]thiophen-4-amine, molecular formula is C8H7NS

Processes for preparation of Brexpiprazole, intermediates used during preparation, and polymorphs of Brexpiprazole are provided.

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Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

17402-83-4, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 17402-83-4, molcular formula is C8H7NS, introducing its new discovery.

Disclosed are azaindazole compounds of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: X is O and Y is N; or X is S and Y is CH; Z is CR2 or N; Q is a heteroaryl; and R1 is defined herein. Also disclosed are methods of using such compounds in the treatment of at least one CYP 17 associated condition, such as, for example, cancer, and pharmaceutical compositions comprising such compounds.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, 17402-83-4, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 17402-83-4

Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. Computed Properties of C8H7NS, In an article, mentioned the application of 17402-83-4, Name is Benzo[b]thiophen-4-amine, molecular formula is C8H7NS

Provided are a pyrimidinyl amino compound having protein kinase inhibitor activity, and a pharmaceutical composition containing said compound; also provided are a use and application of said compound. What is provided is selected from a group consisting of the compound represented by formula (I), a stereoisomer thereof, a tautomer thereof, a pharmacologically acceptable salt thereof, a solvate thereof, and a prodrug thereof. The described compound has good inhibitory activity against the JAK family of kinases and the SYK family of kinases, and therefore may serve as a JAK inhibitor and SYK inhibitor, and is effective in use for the prevention or treatment of diseases related to the JAK and SYK families of kinases.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Chemistry is traditionally divided into organic and inorganic chemistry. category: benzothiophene, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 17402-83-4

The present invention provides a new method for preparing according to […], which belongs to the technical field of pharmaceutical and chemical synthesis. It solves the problem that the existing according to[…] of the preparation method of the impurity is high, the yield is low, the problem of serious pollution. This method, in order to 4-hydroxybenzene and thiophene as the starting material 4 is prepared by the step of reaction intermediates V, to 7-hydroxy-2-quinolone by 2 VII is prepared by the step of reaction intermediates, intermediate V and intermediates prepared by condensation VII clinical medicine […]according to. The raw materials of this invention is easy to obtain, the price is low, the operation is simple, mild reaction conditions, has excellent industrial application value. (by machine translation)

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Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. category: benzothiophene. Introducing a new discovery about 17402-83-4, Name is Benzo[b]thiophen-4-amine

Disclosed are compounds having the formula: or a salt thereof, wherein A, n, R1, R1A, and R2 are as defined herein, and methods of making and using the same

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.category: benzothiophene, you can also check out more blogs about17402-83-4

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Related Products of 17402-83-4, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.17402-83-4, Name is Benzo[b]thiophen-4-amine, molecular formula is C8H7NS. In a article，once mentioned of 17402-83-4

PROCESS FOR THE PREPARATION OF BREXPIPRAZOLE AND INTERMEDIATES THEREOF

The present invention relates to Brexpiprazole having a purity of about 99.5% or more by area percentage of HPLC, having total impurities not more than 0.5% relative to brexpiprazole as measured by area percentage of HPLC, and having less than 0.1% 1-(benzo[b]thiophen-4-yl)piperazine or a salt thereof relative to brexpiprazole by area percentage of HPLC. The present invention also provides a composition comprising brexpiprazole having 1-(benzo[b]thiophen-4-yl)-piperazine or a salt thereof in an amount less than about 0.1% relative to brexpiprazole by area percentage of HPLC and process for the preparation of brexpiprazole.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 17402-83-4

Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

17402-83-4, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In a patent, 17402-83-4, molecular formula is C8H7NS, introducing its new discovery.

Herbicides

The invention provides certain herbicidal thiazolotriazole sulphonamides, processes for their preparation, and compositions containing them, the compounds being of the formula: STR1 where: R1 and R2, which may be the same or different, each represent hydrogen, hydroxy, halo, cyano, substituted or unsubstituted alkyl, alkoxy, alkenyloxy, alkynyloxy, aryl, aralkyl, heteroaryl or carbamoyl, or a group –CORa or –CO2 Ra or where Ra is hydrogen or alkyl; or R1 and R2 together represent an alkylene chain of 3 or 4 carbon atoms; R3 represents a substituted or unsubstituted aryl, heterocyclyl or benzheterocyclyl group; and R4 represents hydrogen, an alkali-metal atom, an ammonium group, a substituted or unsubstituted alkyl, alkenyl, alkynyl, acyl, alkoxycarbonyl or aralkyl group, a heterocyclic group, or a group of the formula: STR2 where R1 and R2 are as defined hereinbefore.

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Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem