Category: 1468-83-3

Zhuang, Shi-Yi published the artcileCopper-catalyzed Oxidative C(sp3)-H/C(sp3)-H Cross-Coupling Reaction of 3-Methylbenzo[c]isoxazoles with Methyl Ketones: Access to Indigoid Analogues, Product Details of C6H6OS, the main research area is aryl methylketone benzoxazole copper tandem ring opening aza Michael; oxoindolinylidene ketone diastereoselective preparation.

A copper-catalyzed oxidative C(sp3)-H/C(sp3)-H cross-coupling reaction of Me ketones and 3-methylbenzo[c]isoxazoles was developed for the direct synthesis of 3-oxoindolin-2-ylidene derivatives This process involved an intermol. nucleophilic addition/ring-opening/aza-Michael addition cascade, providing indigoid analogs with high atom economy and as single isomers exclusively under mild conditions.

Journal of Organic Chemistry published new progress about Alkyl aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Product Details of C6H6OS.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Zhuang, Shi-Yi published the artcileCopper-catalyzed Reaction of Anthranils with Methyl Ketones: Site-Selective C5-Dicarbonylation of Anthranils, Synthetic Route of 1468-83-3, the main research area is diketone preparation regioselective; anthranil aryl methyl ketone dicarbonylation copper catalyst.

A copper-catalyzed site-selective C5-dicarbonylation reaction of 2,1-benzisoxazole has been developed for synthesis of 1,2-dicarbonyl compounds RC(O)C(O)R1 (R = C6H5, 4-FC6H4, 2-thienyl, etc.; R1 = 4-amino-3-formylphenyl) using Me ketones RC(O)Me as a com. available carbonylation reagent. This process represents the first example to implement the C5-dicarbonylation of anthranils, which involves an oxidative Csp3-H/Csp2-H cross-coupling reaction along with thermolytic N-O bond cleavage.

Advanced Synthesis & Catalysis published new progress about Alkyl aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Synthetic Route of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Zhou, You published the artcileI2-Promoted site-selective C-C bond cleavage of aryl methyl ketones as C1 synthons for constructing 5-acyl-1H-pyrazolo[3,4-b]pyridines, Application In Synthesis of 1468-83-3, the main research area is aryl methyl ketone aminopyrazole enaminone iodine cleavage cyclization; pyrazolopyridine regioselective preparation.

A novel iodine promoted [1 + 3 + 2] cleavage cyclization reaction for the synthesis of 1H-pyrazolo[3,4-b]pyridines from aryl Me ketones, 5-aminopyrazoles and enaminones was established. This transition metal-free catalysis method has simple reaction conditions and good substrate compatibility, and was demonstrated in the transformation of alkyl and natural mol.-derived enaminones. Mechanistic studies showed that two cyclization pathways affording different key intermediates were involved, but affording the same target product after site-selective cleavage of the unstrained C-C bond of the acyl group.

Organic Chemistry Frontiers published new progress about Alkyl aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Application In Synthesis of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Qin, Zemin published the artcileCo(II)-Catalyzed Oxidation of N,N-Dimethylaminoethanol: An Efficient Synthesis of Unsymmetrical (2,4-) and Symmetrical (2,6-) Diarylpyridines through Annulation of Aromatic Ketones with a Nitrogen Source, SDS of cas: 1468-83-3, the main research area is diarylpyridine preparation; aromatic ketone dimethylaminoethanol pseudo multicomponent one pot annulation.

An efficient and facile synthesis of 2,4- and 2,6-diarylpyridines has been developed. It involves one-pot [2+2+1+1] pseudo four-component annulation of aromatic ketones, a nitrogen source and a carbon donor. N,N-Dimethylaminoethanol is oxidized in the presence of Co(II) to provide a carbon synthon. Two C-C and two C-N bonds are formed during the oxidative annulation process. The products are strictly controlled due to the steric hindrance: 2,4-diarylpyridines are afforded effectively with small ketones while 2,6-diaryl analogs predominate when bulky ketones are employed.

Asian Journal of Organic Chemistry published new progress about Alkyl aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, SDS of cas: 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Tian, Qing published the artcileSynthesis of quinazolin-4(3H)-ones via electrochemical decarboxylative cyclization of α-keto acids with 2-aminobenzamides, Quality Control of 1468-83-3, the main research area is aryl quinazolinone green preparation; alpha keto acid aminobenzamide electrochem decarboxylative cyclization.

Herein, an environmentally benign electrochem. protocol had been disclosed for the synthesis of quinazolin-4(3H)-one derivatives I [Ar = 3-thienyl, Ph, 2-naphthyl, etc.; R1 = H, 7-F, 7-Cl, 7-Me, 6-Me, 6-MeO; R2 = H, Me, Ph, etc.] from readily available α-keto acids and 2-aminobenzamides. This decarboxylative cyclization process proceeded conveniently in the absence of any homogeneous metal catalysts, bases, or external oxidants. This protocol also featured CO2 byproducts, mild reaction conditions (room temperature and air atm.), and a wide variety of substrate scope, including an array of 2,3-disubstituted quinazolinone products I [Ar = Ph; R1 = H; R2 = n-Bu, iso-Bu, Ph, 2-MeC6H4, Bn, phenethyl].

Molecular Catalysis published new progress about Anhydrides, cyclic Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Quality Control of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Sun, Lincong published the artcileRhodium(III)-catalyzed asymmetric [4+1] spiroannulations of O-pivaloyl oximes with α-diazo compounds, COA of Formula: C6H6OS, the main research area is spirocyclic imine preparation enantioselective; pivaloyl oxime diazo homophthalimide spirocyclization rhodium catalyst.

Chiral Rh (III) catalysts can catalyze the asym. [4+1] spiroannulation of O-pivaloyl oximes with α-diazo homophthalimides under redox-neutral and acid/base-neutral conditions, leading to formation of chiral spirocyclic imines as a result of C-H activation and N-O cleavage. The reaction proceeded with high efficiency and features broad substrate scope, mild reaction conditions, and high to excellent enantioselectivities.

Chemical Communications (Cambridge, United Kingdom) published new progress about Cyclic imines Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, COA of Formula: C6H6OS.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Zhao, Jinwu published the artcileMetal-Free Synthesis of Imidazo[2,1-b]thiazoles from Thioimidazoles and Ketones Mediated by Selectfluor, Related Products of benzothiophene, the main research area is imidazole thiazole preparation thioimidazole ketone Selectfluor.

This paper presents a practical and efficient strategy for the preparation of imidazol[2,1-b]-thiazoles from thioimidazoles and ketones mediated by Selectfluor. The proposed mechanism suggests that this transformation took place through electrophilic thiolation at an α-carbon of ketones by sulfur cation, which was produced by the oxidation of thioimidazole by Selectfluor. This metal-free protocol tolerated various ketones, including Me ketones or non-Me ketones, aryl ketones or aliphatic ketones. Steric hindrance of the substituents at the α-position of ketones or on the aromatic ring of aryl ketones had significant influence on the yields of imidazol[2,1-b]-thiazoles. Thioimidazole and benzothioimidazoles were well tolerated while 5-substituted benzothioimidazoles provided the mixture of the corresponding 6-substituted and 7-substituted benzoimidazo[2,1-b]thiazole products.

European Journal of Organic Chemistry published new progress about Aliphatic ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Related Products of benzothiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Chakraborty, Gargi published the artcileDehydrogenative Synthesis of Quinolines, 2-Aminoquinolines, and Quinazolines Using Singlet Diradical Ni(II)-Catalysts, HPLC of Formula: 1468-83-3, the main research area is quinoline biomimetic synthesis; aminoquinoline biomimetic synthesis; quinazoline biomimetic synthesis; nickel complex diamine singlet diradical oxidative condensation coupling catalyst.

Simple, straightforward, and atom economic methods for the synthesis of quinolines, 2-aminoquinolines, and quinazolines via biomimetic dehydrogenative condensation/coupling reactions, catalyzed by well-defined inexpensive and easy to prepare singlet diradical Ni(II)-catalysts featuring two antiferromagnetically coupled singlet diradical diamine type ligands are described. Various polysubstituted quinolines, 2-aminoquinolines, and quinazolines were synthesized in moderate to good yields from different low-cost and readily accessible starting materials. Several control experiments were carried out to get insight into the reaction mechanism which shows that the nickel and the coordinated diamine ligands participate in a synergistic way during the dehydrogenation of alcs.

Journal of Organic Chemistry published new progress about Acetonitriles Role: RCT (Reactant), RACT (Reactant or Reagent) (phenylacetonitriles). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, HPLC of Formula: 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Li, Jianing published the artcileVisible-Light-Driven Oxidative Cleavage of Alkenes Using Water-Soluble CdSe Quantum Dots, Related Products of benzothiophene, the main research area is cadmium selenide quantum dot preparation; alkene cadmium selenide catalyst oxidative cleavage; carbonyl compound preparation; aryl sulfide cadmium selenide catalyst photooxidation; sulfoxide preparation; CdSe; alkene oxidation; photocatalysis; quantum dots; sulfide oxidation.

The oxidative cleavage of C=C bonds is an important chem. reaction, which is a popular reaction in the photocatalytic field. However, high catalyst-loading and low turnover number (TON) are general shortcomings in reported visible-light-driven reactions. Herein, the direct oxidative cleavage of C=C bonds through water-soluble CdSe quantum dots (QDs) is described under visible-light irradiation at room temperature with high TON (up to 3.7×104). Under the same conditions, water-soluble CdSe QDs could also oxidize sulfides to sulfoxides with 51-84% yields and TONs up to 3.4×104. The key features of this photocatalytic protocol include high TONs, wide substrates scope, low catalyst loadings, simple and mild reaction conditions, and mol. O2 as the oxidant.

ChemSusChem published new progress about Aromatic compounds, sulfoxides Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Related Products of benzothiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Wang, Yutong published the artcileEffect of lipid on formation of Maillard and lipid-Maillard meaty flavor compounds in heated cysteine-xylose-methyl linoleate system, Product Details of C6H6OS, the main research area is cysteine xylose methyl linoleate lipid Maillard meaty flavor compound.

The effect of lipid level and reaction temperature and time on the heated cysteine-xylose reaction to form meaty flavors was investigated. The presence of 1% or 2% Me linoleate inhibited the formation of volatile sulfur-containing compounds and heterocyclic compounds via the Maillard reaction, that is Maillard compounds However, the former was better because of the moderate inhibition and more compounds generated from the lipid-Maillard interaction, that is lipid-Maillard compounds Partial least squares-discriminant anal. suggested the lipid-Maillard compounds were the main markers during varying dosage of Me linoleate, reaction temperature (100-140°C) and reaction time (30-180 min). Lower temperatures increased formation of the Maillard compounds (eg, 2-furfurylthiol) or lipid-Maillard compounds (eg, 2-pentylpyridine) with reaction time. However, high temperatures caused their amounts changed in a curve or irregularly due to the complications from the Maillard and lipid oxidization reactions. By comparing time-courses of the levels of cysteine and Cys-Amadori compounds, and 294 and 420 nm UV absorbance values in the reaction systems under 120°C with or without 2% Me linoleate, it was revealed that the underlying lipid effect mechanism was to initially inhibit and later attend the Maillard reaction, leading to less formation of the Maillard compounds and generation of the lipid-Maillard compounds

Flavour and Fragrance Journal published new progress about Heterocyclic compounds Role: TEM (Technical or Engineered Material Use), USES (Uses). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Product Details of C6H6OS.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem