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1196-19-6, The synthetic route of 1196-19-6 has been constantly updated, and we look forward to future research findings.

1196-19-6, 3-(Bromomethyl)benzo[b]thiophene is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Step 1 Production of ((benzothiophene-3-yl)methyl)(4-methoxy-2-nitrophenyl)amine 740 mg (2.8 mmol) of 4-methoxy-2-nitrotrifluoroanilide were dissolved in 5 ml of dimethylformamide followed by the sequential addition of503 mg (3.64 mmol) of potassium carbonate and 773 mg (3.4 mmol) of 3-bromomethylbenzothiophene and heating to 100C. After 12 hours, 5 ml of 5 M aqueous sodium hydroxide solution were added and refluxed, as is, for 1 hour. After 15 minutes, the solution was cooled to room temperature followed by the addition of 10 ml of water and extraction with chloroform. After washing the organic phase twice with 25 ml of saturated brine and drying with magnesium sulfate, it was concentrated and dried under reduced pressure. The residue was then purified by silica gel column chromatography (hexane:ethyl acetate = 60:1) to obtain 400 mg of ((benzothiophene-3-yl)methyl)(4-methoxy-2-nitrophenyl)amine in the form of an orange powder (yield: 44%).

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Reference:
Patent; TEIJIN LIMITED; EP1249450; (2002); A1;,
Benzothiophene – Wikipedia
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Chemistry is traditionally divided into organic and inorganic chemistry. category: benzothiophene, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 1196-19-6

A simple yet powerful strategy for the molecular design of chiral phase-transfer catalysts: Conformationally flexible, N-spiro chiral quaternary ammonium bromides of type 1 have been newly designed and are found to exert high chiral efficiency by taking advantage of the considerable difference of activity between the diastereomeric homo- and heterochiral isomers through rapid conformational interconversion.

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Synthetic Route of 1196-19-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1196-19-6, Name is 3-(Bromomethyl)benzo[b]thiophene, molecular formula is C9H7BrS. In a Article,once mentioned of 1196-19-6

A variety of methylarenes were successfully converted into the corresponding aromatic nitriles in good to moderate yields by the treatment with NBS or DBDMH in the presence of a catalytic amount of AIBN or BPO, followed by the reaction with molecular iodine in aq NH3 in a one-pot procedure. The present reaction is a useful and practical transition-metal-free method for the preparation of aromatic nitriles from methylarenes.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. name: 3-(Bromomethyl)benzo[b]thiophene, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 1196-19-6, in my other articles.

As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 1196-19-6, name is 3-(Bromomethyl)benzo[b]thiophene. In an article,Which mentioned a new discovery about 1196-19-6, name: 3-(Bromomethyl)benzo[b]thiophene.

Substituted histidine compounds of formula (I) are described as well as methods for the preparation and pharamaceutical compositions of same, which are useful as inhibitors of protein famesyltransferase and for the treatment of proliferative diseases including cancer, restenosis, and psoriasis, and as antiviral agents. STR1

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. name: 3-(Bromomethyl)benzo[b]thiophene, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 1196-19-6, in my other articles.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. Product Details of 1196-19-6, In an article, mentioned the application of 1196-19-6, Name is 3-(Bromomethyl)benzo[b]thiophene, molecular formula is C9H7BrS

Virtually complete chirality transfer has been realized in the N-terminal alkylation of small, Schiff-base activated peptides under mild phase-transfer conditions, in which finely tuned chiral quaternary ammonium salts are used as catalysts. Repeated extension and alkylation of the N-terminal position can lead selectively to nonnatural oligopeptides (see picture).

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 1196-19-6. In my other articles, you can also check out more blogs about 1196-19-6

Related Products of 1196-19-6, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1196-19-6, Name is 3-(Bromomethyl)benzo[b]thiophene, molecular formula is C9H7BrS. In a Patent,once mentioned of 1196-19-6

The present invention is directed to novel processes for the preparation of sulfamide derivatves, useful in the treatment of epilepsy and related disorders.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Extracurricular laboratory:new discovery of 3-(Bromomethyl)benzo[b]thiophene

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1196-19-6, Name is 3-(Bromomethyl)benzo[b]thiophene, belongs to benzothiophene compound, is a common compound. Quality Control of 3-(Bromomethyl)benzo[b]thiopheneIn an article, once mentioned the new application about 1196-19-6.

Using a variety of alpha-hydroxy hydroxamic acid derivatives, the size and shape of the S1′ pocket for the CD23 processing metalloprotease has been explored. It has been demonstrated that a P1′ 2-naphthylmethyl group occupies most of the available space and gives excellent selectivity against fibroblast collagenase (matrix metalloproteinase-1, MMP-1) and other MMPs.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

More research is needed about 3-(Bromomethyl)benzo[b]thiophene

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Reference of 1196-19-6, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 1196-19-6, Name is 3-(Bromomethyl)benzo[b]thiophene,introducing its new discovery.

A series of indole, 7-azaindole, benzofuran, and benzothiophene compounds have been prepared and evaluated for affinity at D2-like dopamine receptors. These compounds share structural elements with the classical D 2-like dopamine receptor antagonists haloperidol, N-methylspiperone and benperidol. Two new compounds, 4-(4-iodophenyl)-1-((4-methoxy-1H-indol-3-yl) methyl)piperidin-4-ol (6) and 4-(4-iodophenyl)-1-((5-methoxy-1H-indol-3-yl) methyl)piperidin-4-ol (7), were found to have high affinity to and selectivity for D2 versus D3 receptors. Changing the aromatic ring system from an indole to other heteroaromatic ring systems reduced the D 2 binding affinity and the D2 versus D3 selectivity.

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Reference:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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Application of 1196-19-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.1196-19-6, Name is 3-(Bromomethyl)benzo[b]thiophene, molecular formula is C9H7BrS. In a article,once mentioned of 1196-19-6

Thiophene and benzothiophene ligands containing N-heterocyclic carbene (NHC) moieties were used to synthesize five and six-membered Pt(II) metallacycles. Ligand scaffolding was synthesized using two methods. The ligands were synthesized using a coupling reaction, utilizing Cu2O as the catalyst or were synthesized using a nucleophilic substitution reaction. The ligands were then metalated by chelate-assisted C?H activation. The synthesis, characterization, reactivity, and photophysical properties of these NHC-functionalized, cyclometalated products are reported.

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Reference:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 1196-19-6. In my other articles, you can also check out more blogs about 1196-19-6

Synthetic Route of 1196-19-6, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1196-19-6, Name is 3-(Bromomethyl)benzo[b]thiophene, molecular formula is C9H7BrS. In a Patent,once mentioned of 1196-19-6

The present invention is a thiobenzimidazole derivative represented by the following formula (1) [image] or a medically acceptable salt thereof wherein said thiobenzimidazole derivative and a medically acceptable salt thereof have a potent activity of inhibiting human chymase. Thus, they are potential preventive and/or therapeutic agents clinically applicable to various diseases in which human chymase is involved.

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Reference:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem