Category: 1195-14-8

Correction to “Predicting Flash Points of Pure Compounds and Mixtures with COSMO-RS” [Erratum to document cited in CA164:106271] was written by Reinisch, Jens;Klamt, Andreas. And the article was included in Industrial & Engineering Chemistry Research in 2016.Name: 2-Methylbenzo[b]thiophene This article mentions the following:

The final conversion within eq 4 in the original manuscript is incorrect; The correct equation has been given. There is an analog error in eq 11; The corrected equation has been given. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Name: 2-Methylbenzo[b]thiophene).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Name: 2-Methylbenzo[b]thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Toluene dioxygenase-catalyzed cis-dihydroxylation of benzo[b]thiophenes and benzo[b]furans: synthesis of benzo[b]thiophene 2,3-oxide was written by Boyd, Derek R.;Sharma, Narain D.;Brannigan, Ian N.;Evans, Timothy A.;Haughey, Simon A.;McMurray, Brian T.;Malone, John F.;McIntyre, Peter B. A.;Stevenson, Paul J.;Allen, Christopher C. R.. And the article was included in Organic & Biomolecular Chemistry in 2012.Quality Control of 2-Methylbenzo[b]thiophene This article mentions the following:

Enzymic cis-dihydroxylation of benzo[b]thiophene, benzo[b]furan and several Me substituted derivatives was found to occur in both the carbocyclic and heterocyclic rings. Relative and absolute configurations and enantiopurities of the resulting dihydrodiols were determined Hydrogenation of the alkene bond in carbocyclic cis-dihydrodiols and ring-opening epimerization/reduction reactions of heterocyclic cis/trans-dihydrodiols were also studied. The relatively stable heterocyclic dihydrodiols of benzo[b]thiophene and benzo[b]furan showed a strong preference for the trans configuration in aqueous solutions The 2,3-dihydrodiol metabolite of benzo[b]thiophene was utilized as a precursor in the chemoenzymic synthesis of the unstable arene oxide, benzo[b]thiophene 2,3-oxide. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Quality Control of 2-Methylbenzo[b]thiophene).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Quality Control of 2-Methylbenzo[b]thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Determination of individual sulfur-containing compounds in gas condensate and petrol by gas chromatography was written by Afanas’ev, I. P.;Gorshkova, T. A.;Arystanbekova, S. A.;Lapina, M. S.;Volynskii, A. B.. And the article was included in Journal of Analytical Chemistry in 2017.Reference of 1195-14-8 This article mentions the following:

A procedure is developed for the determination of more than 60 individual sulfur-containing compounds (SCC) in liquid hydrocarbon raw materials and in liquid fuels using gas chromatog. on a 25-m WCOT column, inner diameter 0.32 mm, with a nonpolar dimethylpolysiloxane stationary phase (layer thickness 5 μm) and chemiluminescence detection. SCC were identified by individual standard substances and published data. Quant. determination was carried out by the internal standard method. The results of determination of individual SCC in petrol and stable gas condensate are presented. The most high-boiling SCC found in significant amounts (more than 0.005 wt % of sulfur) were C₂-benzothiophenes (in petrol) and C₄-dibenzothiophenes (in gas condensate). In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Reference of 1195-14-8).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Reference of 1195-14-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Gold-catalyzed intermolecular alkyne oxyarylation for C3 functionalization of benzothiophenes was written by Rist, Paige A.;Grainger, Richard S.;Davies, Paul W.. And the article was included in Organic Letters in 2021.Application of 1195-14-8 This article mentions the following:

C3-selective C-C bond formation on benzothiophenes is challenging, and few direct functionalization methods are available. A gold-catalyzed reaction of alkynes with benzothiophene S-oxides provides regioselective entry into C3-alkylated benzothiophenes with the C7-alkylated isomer as the minor product. This oxyarylation reaction works with alkyl and aryl alkynes and substituted and unsubstituted benzothiophenes. Mechanistic studies identify that sulfoxide inhibits the catalyst [DTBPAu(PhCN)]SbF₆, which also degrades and forms the unreactive complex [(DTBP)₂Au]SbF₆. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Application of 1195-14-8).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Application of 1195-14-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Niobium(V) oxido tris-carbamate as easily available and robust catalytic precursor for the selective sulfide to sulfone oxidation was written by Bresciani, Giulio;Gemmiti, Mario;Ciancaleoni, Gianluca;Pampaloni, Guido;Marchetti, Fabio;Crucianelli, Marcello. And the article was included in Molecular Catalysis in 2021.HPLC of Formula: 1195-14-8 This article mentions the following:

The oxidation of the sulfide function promoted by a variety of vanadium compounds has been largely explored, whereas the use of homogeneous catalytic systems based on the heavier group 5 metals remains less explored. We report the use of easily available niobium and tantalum carbamates, i.e. [M(O₂CNMe₂)₅] (M = Nb, 1; M = Ta, 2), [Nb(O₂CNMe₂)₄], 3, [NbO(O₂CNEt₂)₃], 4, and [NbCl₃(O₂CNEt₂)₂], 5, as effective catalysts for the conversion of a series of alkyl aryl and aromatic sulfides into the corresponding sulfones. NMR investigations on the performant niobium catalyst 4 unexpectedly revealed the substantial stability of this compound in the protic catalytic environment, and a plausible catalytic cycle was obtained by DFT studies. The two active catalytic species, i.e. 4 and its minor mono-methoxide derivative, presumably interconvert to each other exploiting the versatile coordination of the carbamato ligand. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8HPLC of Formula: 1195-14-8).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.HPLC of Formula: 1195-14-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Hierarchical TS-1 zeolite as an efficient catalyst for oxidative desulphurization of hydrocarbon fractions was written by Serrano, D. P.;Sanz, R.;Pizarro, P.;Moreno, I.;Medina, S.. And the article was included in Applied Catalysis, B: Environmental in 2014.Related Products of 1195-14-8 This article mentions the following:

The catalytic oxidative desulphurization (ODS) of S-containing aromatic compounds has been investigated over a hierarchical TS-1 zeolite prepared from silanized protozeolitic units, characterized by having, addnl. to the zeolitic micropores, a secondary porosity within the supermicro/mesopore region. A standard TS-1 sample has been employed as reference catalyst. The influence of both the solvent (n-heptane and acetonitrile) and the oxidizing agent (hydrogen peroxide and tert-butylhydroperoxide, TBHP) was first studied using dibenzothiophene (DBT) as model substrate. In all cases, the catalytic activity exhibited by the hierarchical TS-1 was much higher than that obtained with the conventional TS-1 as a consequence of the improved accessibility caused by the presence of the secondary porosity. A very high desulphurization activity was obtained with the combination of heptane and TBHP, as solvent and oxidant, resp., leading to an almost total DBT conversion. This fact has been attributed to the fully miscibility of the oxidant solution (TBHP in decane) in the organic reaction medium. Moreover, it is noteworthy that, in these conditions, the oxidation product (sulfone) is insoluble in the reaction medium, which facilitates its removal by filtration or centrifugation. Addnl., the oxidation of different aromatic organosulfur compounds [benzothiophene (BT), 2-methylbenzothiophene (2-MBT), 2,5-dimethylthiophene (2,5-DMT) and dibenzothiophene (DBT)] was investigated using the hierarchical TS-1 catalyst. The trend in the conversion values obtained was 2,5-DMT < BT < 2-MBT < DBT. These results indicate that the oxidation conversion is determined by the nucleophilic character of the sulfur atom, and not by the mol. size of the S-containing compound, provided that the steric and diffusional limitations are overcome by the presence of the hierarchical TS-1 porosity. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Related Products of 1195-14-8).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is also used in the manufacturing of dyes such as thioindigo.Related Products of 1195-14-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Reversible Photomodulation of Electronic Communication in a π-Conjugated Photoswitch-Fluorophore Molecular Dyad was written by Moreno, Javier;Schweighoefer, Felix;Wachtveitl, Josef;Hecht, Stefan. And the article was included in Chemistry – A European Journal in 2016.Application In Synthesis of 2-Methylbenzo[b]thiophene This article mentions the following:

The extent of electronic coupling between a boron dipyrromethene (BODIPY) fluorophore and a diarylethene (DAE) photoswitch has been modulated in a covalently linked mol. dyad by irradiation with either UV or visible light. In the open isomer, both moieties can be regarded as individual chromophores, while in the closed form the lowest electronic (S₀→S₁) transition of the dyad is slightly shifted, enabling photomodulation of its fluorescence. Transient spectroscopy confirms that the dyad behaves dramatically different in the two switching states: while in the open isomer it resembles an undisturbed BODIPY fluorophore, in the closed isomer no fluorescence occurs and instead a red-shifted DAE behavior prevails. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Application In Synthesis of 2-Methylbenzo[b]thiophene).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Application In Synthesis of 2-Methylbenzo[b]thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Palladium-Catalyzed Intermolecular Arylcarbonylation of Unactivated Alkenes: Incorporation of Bulky Aryl Groups at Room Temperature was written by Li, Xiang;Chen, Pinhong;Liu, Guosheng. And the article was included in Angewandte Chemie, International Edition in 2018.Electric Literature of C9H8S This article mentions the following:

A palladium-catalyzed intermol. arylcarbonylation of unactivated alkenes was developed. Unsym. diaryliodonium salts (DAISs) were used as arylation reagents, the bulky aryl group (ArL) of which was exclusively incorporated into the arylcarbonylated products, which contained the ArL group and a carboxylic ester group at the α- and β-carbon position, resp., of the original terminal C-C double bond. The reaction featured excellent chemo- and regioselectivity, high functional-group tolerance, and very mild reaction conditions. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Electric Literature of C9H8S).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Electric Literature of C9H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

On the use of diarylmaleimide derivatives in biological contexts: An investigation of the photochromic properties in aqueous solution was written by Fleming, Cassandra;Remon, Patricia;Li, Shiming;Simeth, Nadja Anita;Koenig, Burkhard;Groetli, Morten;Andreasson, Joakim. And the article was included in Dyes and Pigments in 2017.Related Products of 1195-14-8 This article mentions the following:

A series of photochromic diarylmaleimide derivatives has been synthesized and studied with respect to the photochromic properties in aqueous solution The main rationale is to investigate if these compounds could be used as photoswitchable units in biol. contexts, motivated by the fact that the diarylmaleimide structural motif is identified in many pharmacophores. Thus, photoswitchable variants of this class of compounds could be very useful in the quest for photoactivatable drugs. The photoinduced cyclization reaction (colorization) is suppressed in solvents of high polarity, whereas the ring-opening reaction (decolorization) still occurs with high efficiency. The photochromically active anti-parallel conformer of the open form is more abundant in the asym. substituted derivatives, which in turn favors the formation of the closed isomeric form. The rates of the thermal isomerization reactions have also been assessed, together with the resistance toward thermal degradation Here it was observed that the maleimide derived compounds were not susceptible to the thermally driven reactions (hydrolysis and isomerization). In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Related Products of 1195-14-8).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is also used in the manufacturing of dyes such as thioindigo.Related Products of 1195-14-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem