Product Details of 1034305-11-7, Chemical research careers are more diverse than they might first appear, as there are many different reasons to conduct research and many possible environments. In a article, 1034305-11-7, molcular formula is C15H10BrFOS, introducing its new discovery.
A series of C-glucosides with various heteroaromatics has been synthesized and its inhibitory activity toward SGLTs was evaluated. Upon screening several compounds, the benzothiophene derivative (14a) was found to have potent inhibitory activity against SGLT2 and good selectivity versus SGLT1. Through further optimization of 14a, a novel benzothiophene derivative (14h; ipragliflozin, ASP1941) was discovered as a highly potent and selective SGLT2 inhibitor that reduced blood glucose levels in a dose-dependent manner in diabetic models KK-Ay mice and STZ rats.
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Reference:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem