20699-85-8, Methyl 5-aminobenzo[b]thiophene-2-carboxylate is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Production Example 4012240] A mixture of 300 mg of methyl 5-aminobenzo[b] thiophene-2-carboxylate, 310 g of 1 -ethyl-3-(3-dimethylami- nopropyl)carbodiimide hydrochloride, 294 mg of benzoic acid, 18.4 mg of N,N-dimethyl-4-aminopyridine, and 20 ml of tetrahydrofuran was stirred for 24 hours at room temperature. The reaction mixture was concentrated under reduced pressure, and tert-butyl methyl ether was added to the residues. The organic layer was washed with a 1 M aqueous hydrochloric acid solution, a 1 M aqueous sodium hydrogen carbonate solution, and saturated saline, dried over magnesium sulfate, and concentrated under reduced pressure, thereby obtaining 318 mg of methyl 5-benzoylaminobenzo [b]thiophene-2-carboxylate (hereinafier, described as a ?compound 68 of the present invention?). 12241] Compound 68 of the Present Invention12242] ?H-NMR (CDC13) oe: 8.40 (br s, 1H), 8.05 (s, 1H),7.91-7.90 (m, 3H), 7.86-7.84 (m, 1H), 7.58-7.53 (m, 4H),3.96 (s, 3H).
20699-85-8, The synthetic route of 20699-85-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SUMITOMO CHEMICAL COMPANY, LIMITED; Mukumoto, Fujio; Tamaki, Hiroaki; Kusaka, Shintaro; Iwakoshi, Mitsuhiko; US2015/282482; (2015); A1;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem