35212-85-2, Methyl 3-aminobenzo[b]thiophene-2-carboxylate is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A. 3-Aminobenzothiophene (20A) To a solution of 3-amino-benzo[b]thiophene-2-carboxylic acid, methyl ester (1 g, 4.83 mmol, 1 eq) in 1-methyl-2-pyrrolidinone (8 mL) was added piperazine (2.08 g, 24.13 mmol, 5 eq). The reaction was stirred at 130 C. overnight. Ice was added, and the mixture was extracted with ethyl acetate. The organic extracts were washed twice with water, dried, and concentrated in vacuo. The crude material was purified by flash chromatography on silica gel eluding with 40% ethyl acetate in hexanes to provide 600 mg (83%) of Compound 20A as a yellow oil., 35212-85-2
The synthetic route of 35212-85-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Salvati, Mark E.; Balog, James Aaron; Shan, Weifang; Giese, Soren; US2003/114420; (2003); A1;; ; Patent; Salvati, Mark E.; Balog, James Aaron; Shan, Weifang; Giese, Soren; Harikrishnan, Lalgudi S.; US2004/77606; (2004); A1;,
Benzothiophene – Wikipedia
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