A rapid and sensitive procedure for the quantitative determination of plasma amino acids was written by Griffin, Martin;Price, Susan J.;Palmer, Trevor. And the article was included in Clinica Chimica Acta in 1982.Product Details of 32595-59-8 This article mentions the following:
Amino acids were determined by precolumn derivatization with o-phthalaldehyde and 2-mercaptoethanol and separation by reversed-phase high-performance liquid chromatog. The stationary phase was Zorbax C8, and the mobile phase was a gradient of KOAc (0.02M, pH 5.5) containing 1% THF in MeOH:THF (99:1). Thirty amino acids and amines were separated in 27.5 min, with a lower detection limit of <1 pmol. In the experiment, the researchers used many compounds, for example, 2-Amino-3-hydroxy-3-(thiophen-2-yl)propanoic acid (cas: 32595-59-8Product Details of 32595-59-8).
2-Amino-3-hydroxy-3-(thiophen-2-yl)propanoic acid (cas: 32595-59-8) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Product Details of 32595-59-8
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem