Microwave-Assisted Syntheses of Thiophene-Based Ionic Liquids: Structural Design and Optimization was written by Schiel, Maria A.;Domini, Claudia E.;Chopa, Alicia B.;Silbestri, Gustavo F.. And the article was included in Synthesis in 2018.Product Details of 638-02-8 The following contents are mentioned in the article:
This manuscript explores microwave-assisted reactions for the synthesis of new ionic materials involving the S-alkylation of thiophene. All isolatable products have been fully characterized by NMR and all product have been quantified through UV-vis spectroscopy. By means of a design technique, the exptl. protocol (25 min, 200 W, 50 °C) has been optimized, which led us to better yields (96 %). In the absence of MW activation, the conventional thermal reaction at room temperature took longer (24 – 48 h) to obtain similar results. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Product Details of 638-02-8).
2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Product Details of 638-02-8
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem