Chiral acid-catalysed enantioselective C-H functionalization of toluene and its derivatives driven by visible light was written by Li, Fuyuan;Tian, Dong;Fan, Yifan;Lee, Richmond;Lu, Gang;Yin, Yanli;Qiao, Baokun;Zhao, Xiaowei;Xiao, Ziwei;Jiang, Zhiyong. And the article was included in Nature Communications in 2019.Category: benzothiophene The following contents are mentioned in the article:
Here, photoinduced radical-based enantioselective C(sp3)-C(sp3) coupling reactions of activated ketones with toluene and its derivatives by means of chiral acid catalysis was reported. With a La(OTf)3/pybox complex catalyst, a variety of chiral 3-hydroxy-3-benzyl-substituted 2-oxindoles, including many conventionally difficult-to-access variants, are obtained directly from isatins in high yields with good to excellent enantioselectivities. Acenaphthoquinone is also compatible with the use of a chiral phosphoric acid (CPA) catalyst, leading to another series of important enantioenriched tertiary alcs. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Category: benzothiophene).
2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Category: benzothiophene
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem