Wang, Yujiao et al. published their research in Food Additives & Contaminants, Part A in 2020 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Name: 2,5-Dimethylthiophene

Determination of exogenous-prohibited flavour compounds added in coffee using gas chromatography triple quadrupole tandem mass spectrometry and gas chromatography/combustion/isotope ratio mass spectrometry was written by Wang, Yujiao;Liu, Tong;Chen, Fengming;Wang, Xiujuan;Zhang, Feng. And the article was included in Food Additives & Contaminants, Part A in 2020.Name: 2,5-Dimethylthiophene The following contents are mentioned in the article:

An anal. method based on gas chromatog. coupled to triple quadrupole tandem mass spectrometry (GC-MS/MS) was developed for the simultaneous determination of exogenous prohibited flavor compounds in coffee samples. In addition, gas chromatog./combustion/isotope ratio mass spectrometry (GC/C/IRMS) was developed to determine the origin of the founded prohibited flavor compound, N-methylpyrrole-2-carboxaldehyde (NMPCA). The good selectivity and sensitivity achieved in multiple reactions monitoring (MRM) mode allowed satisfactory confirmation and quantitation for the flavor compounds The limits of detection (LODs) and limits of quantitation (LOQs) of these compounds were in the range of 0.0005-5.0μg/kg and 0.002-16.0μg/kg, resp. The coffee samples were extracted with simultaneous distillation extraction (SDE) and NMPCA was analyzed on a GC/C/IRMS system. The δ13C values of endogenous NMPCA in coffee beans were within a range of -35.0% to -31.1%, whereas exogenous NMPCA was the range from -27.9% to -23.9%. The validation results revealed that the GC-MS/MS method was sensitive and reliable, and the origin of NMPCA can be distinguished by GC/C/IRMS. Finally, this method was successfully applied to coffee samples anal. and NMPCA was found in coffee samples. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Name: 2,5-Dimethylthiophene).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Name: 2,5-Dimethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem