3541-37-5, Benzo[b]thiophene-2-carboxaldehyde is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
4-Bromophenylacetonitrile (1 g, 5.1 mmol) and benzo[b]thiophene-2-carboxaldehyde (825 mg, 5.1 mmol) are dissolved in 30 mL of dry MeOH and stirred at 0 C for 10 min. Sodium methoxide (380 mg, 7.1 mmol) was added in small portions, and the solution was stirred for 15 min at 0 C and then for 6 h at room temperature. The precipitate was collected by filtration, washed with 10 mL of MeOH, then with water, and dried at 50 C to give the alpha,beta-unsaturated nitrile 3 as a yellow powder (1.55 g, 90%); Rf = 0.36 (cyclohexane/EtOAc, 90:10); mp = 160-162 C; 1H NMR (300 MHz, CDCl3): delta (ppm): 7.37-7.45 (m, 2H), 7.52-7.60 (m, 4H), 7.69 (s, 1H, Hvinyl), 7.82-7.87 (m, 3H); 13C NMR (75 MHz, CDCl3): delta (ppm): 109.68 (C), 117.35 (CN), 122.43 (CH), 123.58 (C), 124.65 (CH), 125.12 (CH), 126.67 (CH), 127.33 (2CH), 130.01 (CH), 132.31 (2CH) 132.86 (C), 134.86 (CH), 137.37 (C), 138.69 (C), 141.28 (C); HRMS (MALDI-TOF): [M]+ calcd for (C17H10BrNS), 338.9717; found, 338.9711.
As the paragraph descriping shows that 3541-37-5 is playing an increasingly important role.
Reference£º
Article; Hafedh, Nesrine; Aloui, Faouzi; Dorcet, Vincent; Barhoumi, Houcine; Comptes Rendus Chimie; vol. 21; 7; (2018); p. 652 – 658;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem