Ullrich, Karl J. published the artcileContraluminal organic anion and cation transport in the proximal renal tubule: V. Interaction with sulfamoyl- and phenoxy diuretics, and with β-lactam antibiotics, SDS of cas: 40180-04-9, the main research area is kidney tubule contraluminal ion transport; xenobiotic ion transport kidney tubule; antibiotic ion transport kidney tubule; diuretic ion transport kidney tubule.
In order to study the interaction of sulfamoyl- and phenoxy-diuretics as well as of β-lactam antibiotics with the contraluminal anion and cation transport systems, the inhibitory potency of these substances against the influx of [3H]p-aminohippurate, [14C]succinate, [35S]sulfate, and [3H]N1-methylnicotinamide into cortical tubular cells were determined The results show that the probenecid, the diuretics furosemide, piretanide, hydrochlorothiazide, acetazolamide, ethacrynic, and tielinic acid, and the β-lactam antibiotics of the penicillin and cephalosporin type interact with the anion and cation transport systems in a predictable fashion.
Kidney International published new progress about Anions. 40180-04-9 belongs to class benzothiophene, name is 2-(2,3-Dichloro-4-(thiophene-2-carbonyl)phenoxy)acetic acid, and the molecular formula is C13H8Cl2O4S, SDS of cas: 40180-04-9.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem