Koga, Hiroshi published the artcileStudies on uricosuric diuretics. 4. Three-dimensional structure-activity relationships and receptor mapping of (aryloxy)acetic acid diuretics, Formula: C13H8Cl2O4S, the main research area is aryloxyacetate diuretic structure activity receptor model.
A receptor model was created for (aryloxy)acetic acid diuretics based on the enhanced diuretic activity of indacrinone (I) and a tienilic acid analog (II) when compared with tienilic acid (III). The degree of fitting to this receptor model was related to the diuretic activity of a series of (aryloxy)acetic acid analogs. Studies with addnl. analogs led to a modification of the receptor model which should be useful for future drug design.
Journal of Medicinal Chemistry published new progress about Diuretics. 40180-04-9 belongs to class benzothiophene, name is 2-(2,3-Dichloro-4-(thiophene-2-carbonyl)phenoxy)acetic acid, and the molecular formula is C13H8Cl2O4S, Formula: C13H8Cl2O4S.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem