Zhuang, Shi-Yi published the artcileI2-DMSO mediated oxidative amidation of methyl ketones with anthranils for the synthesis of α-ketoamides, Recommanded Product: 3-Acetylthiophene, the main research area is formyl iodophenyl oxo arylacetamide preparation; aryl ethanone anthranil oxidative amidation iodine dimethyl sulfoxide mediated.
An I2-DMSO mediated oxidative amidation of Me ketones using anthranils as masked N-nucleophiles had been developed for the direct synthesis of α-ketoamides I [R1 = Ph, 4-MeC6H4, 4-MeOC6H4, etc.; R2 = 4-I, 4-MeO, 3-F-4-I, etc.] with high atom-economy. This metal-free process involved reductive N-O bond cleavage of anthranils and oxidative C-N bond formation of Me ketones under mild conditions. The iodo group and electrophilic formyl group provided multiple possibilities for further functionalization of α-ketoamides I.
Organic & Biomolecular Chemistry published new progress about Amidation (oxidative). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Recommanded Product: 3-Acetylthiophene.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem