Tseitler, T. A. published the artcileSynthesis and Antiglycating Activity of 2-Aminopropylmorpholino-5-Aryl-6H-1,3,4-Thiadiazine Dihydrobromides and 2-Aminopropylmopholino-5-Thienyl-6H-1,3,4-Thiadiazine Dihydrobromides, SDS of cas: 1468-83-3, the main research area is propylmorpholino aryl thiadiazine dihydrobromide preparation antiglycating activity SAR; thienyl propylmorpholino thiadiazine dihydrobromide preparation antiglycating activity SAR.
A group of novel thiadiazine dihydrobromides compounds I [R = Ph, 2-thienyl, 4-chlorophenyl, etc.] were synthesized by cyclocondensation of 4-[3-(4-morpholino)propyl]-3-thiosemicarbazide with α-haloacetoarenones or α-haloacetylthiophenones. Two compounds of this group were found to produce effective inhibition of non-enzymic protein glycation in an in-vitro model system. These test results indicate that compounds I [R = Ph, 4-chlorophenyl] groups at position 5 of the thiadiazine ring resp., were candidates for in-vivo studies.
Pharmaceutical Chemistry Journal published new progress about Antidiabetic agents. 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, SDS of cas: 1468-83-3.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem