In 2019,Oriental Journal of Chemistry included an article by Kasimbi, D.; Reddy, K. Hussain; Devanna, N.. SDS of cas: 88-15-3. The article was titled 《Synthesis, spectral characterization and antibacterial activity of functionalized hydrazones》. The information in the text is summarized as follows:
New hydrazones have been synthesized by condensing 2-acetylthiophene with acetic hydrazide and benzhydrazide. The synthesized hydrazones viz. 2-acetylthiophene acetylhydrazone (ATAH), 2-acetylthiophene benzoylhydrazone (ATBH) were characterized in the light of physicochem. and anal. data. Structures of ATAH and ATBH has been confirmed by FT-IR, 1H-NMR and Mass spectral data. The hydrazones are screened for their anti-bacterial activity against E. coli, Bacillus cereus, Staphylococcus aureus and Pseudomonas aeruginosa. Acetylhydrazones were found to show more antibacterial activity than the corresponding benzoylhydrazones. In addition to this study using 1-Thiophen-2-yl-ethanone, there are many other studies that have used 1-Thiophen-2-yl-ethanone(cas: 88-15-3SDS of cas: 88-15-3) was used in this study.
1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. SDS of cas: 88-15-3
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem