Kaloglu, Murat; Kaloglu, Nazan; Ozdemir, Namik; Ozdemir, Ismail published an article in 2021. The article was titled 《The first use of [PdBr2(imidazolidin-2-ylidene)(pyridine)] catalysts in the direct C-H bond arylation of C2-substituted furan and thiophene》, and you may find the article in Research on Chemical Intermediates.Recommanded Product: 1-Thiophen-2-yl-ethanone The information in the text is summarized as follows:
In this study, four new 1,3-disubstituted imidazolinium salts as NHC ligand precursors I [R = 4-i-Pr, 4-Cl, 3,5-di-Me, 2,3,5,6-tetra-Me], and their four new PEPPSI-type palladium complexes II were synthesized. The structures of all new compounds were fully characterized by different spectroscopic and anal. techniques. The more detailed structural characterization of one of the palladium complexes was determined by single-crystal X-ray diffraction study. The catalytic activities of all palladium complexes were evaluated in the direct C-H bond arylation of 2-acetylfuran and 2-acetylthiophene with (hetero) aryl bromides and readily available and inexpensive aryl chlorides in presence of 1 mol% catalyst loading at 120°C. Under the given conditions, (hetero)aryl halides were successfully applied as the arylating reagents to achieve the C5-arylated furans/thiophenes III [R1 = Ph, 2-thienyl, 2-MeC6H4, etc.; Y = O, S] in acceptable to high yields. The experimental process involved the reaction of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Recommanded Product: 1-Thiophen-2-yl-ethanone)
1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Recommanded Product: 1-Thiophen-2-yl-ethanone
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem