Research speed reading in 2021. We’ll be discussing some of the latest developments in chemical about CAS: Quality Control of 5-Aminobenzothiophene, C8H7NS. A document type is Article, introducing its new discovery., Quality Control of 5-Aminobenzothiophene
This paper describes a facile one-pot protocol to synthesize 2-aminophenol derivatives via a palladium-catalyzed C-H acetoxylation strategy with 5-nitropyrimidine as a directing group (DG), which can be easily preinstalled and readily removed under mild condition after the coupling. In addition, the transformation is operationally simple, has high functional group tolerance, and is amenable to gram-scale. Moreover, several examples were shown that introduction/removal of 5-nitropyrimidine and the C-H oxylation sequence could be integrated in one pot.
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Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem