With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.5381-20-4,Thianaphthene-3-carboxaldehyde,as a common compound, the synthetic route is as follows.
General procedure: To a solution of the appropriate aldehyde or ketone (1 eq.) in 50% aqueous ethanol (v/v), thiosemicarbazide (1 eq.) was added. The mixture was stirred at 60C for 2-12h, cooled at room temperature and diluted with water. The precipitate formed was collected and recrystallized from water and ethanol to give the desired product in 65-95% yield., 5381-20-4
5381-20-4 Thianaphthene-3-carboxaldehyde 227328, abenzothiophene compound, is more and more widely used in various fields.
Reference£º
Article; Linciano, Pasquale; Moraes, Carolina B.; Alcantara, Laura M.; Franco, Caio H.; Pascoalino, Bruno; Freitas-Junior, Lucio H.; Macedo, Sara; Santarem, Nuno; Cordeiro-da-Silva, Anabela; Gul, Sheraz; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Ferrari, Stefania; Luciani, Rosaria; Quotadamo, Antonio; Costantino, Luca; Costi, Maria Paola; European Journal of Medicinal Chemistry; vol. 146; (2018); p. 423 – 434;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem