6287-82-7, Name is 2,3-Dibromobenzo[b]thiophene, belongs to benzothiophene compound, is a common compound. SDS of cas: 6287-82-7In an article, once mentioned the new application about 6287-82-7.
A series of 2,3-diaryldibenzo[b]thiophene derivatives have been synthesized via Suzuki coupling reactions in moderate to good yields (59?79%). The synthesized compounds were evaluated for their antithrombolytic, biofilm inhibition, and hemolytic potential. All compounds showed significant biological potential. Compound (4k) revealed excellent antithrombolytic (87.24%) and biofilm inhibition (99.64%) activity. While compound (4i) exhibited an outstanding hemolytic potential (84.53%). The docking studies uncovered that studied compounds interact with streptokinase and plasminogen via hydrogen bonding, pi-anion, pi?pi stacked interactions, and pi-sigma bonding type interactions. The results revealed that synthesized benzo[b]thiophene derivatives could be a potential source of therapeutic agents.
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Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem