5381-20-4, Thianaphthene-3-carboxaldehyde is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,5381-20-4
General procedure: To a stirred solution of the triphenylphosphonium salt (0.005 mol) and the corresponding aldehyde (0.011 mol) in absolute ethanol (100 mL) the solution of sodium ethoxide (0.253 g, 0.011 mol in 15 mL of absolute ethanol) was added dropwise. The reaction was complete within 3-4 h (usually was left to stand overnight). After removal of the solvent, the residue was worked up with water and benzene. The benzene extracts were dried (anhydrous MgSO4) and concentrated. The crude reaction mixture was purified and the isomers of products 7 and 8 were separated by repeated column chromatography on silica gel using petroleum ether as the eluent. The first fractions yielded cis,cis-, cis,trans- and the last fractions trans,trans-isomers. The data of the new compounds 7a-c and 8a,b are given below. All isomers of 2,2′-(1,2-phenylenedivinylene)dithiophene (7a), 3,3′-(1,2-phenylenedivinylene)dithiophene (8a) and 3,3′-(1,2-phenylenedivinylene)dibenzo[b]thiophene (8b) are separated and described by spectroscopic methods whereas in the case of 7b and 7c only trans,trans-isomers are isolated.
As the paragraph descriping shows that 5381-20-4 is playing an increasingly important role.
Reference£º
Article; Vuk, Dragana; Marini?, ?eljko; Mol?anov, Kre?imir; Koji?-Prodi?, Biserka; ?indler-Kulyk, Marija; Tetrahedron; vol. 68; 34; (2012); p. 6873 – 6880;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem