Synthesis and biological evaluation of some novel pyrazoline derivatives was written by Satyanarayana, D.;Revanasiddappa, B. C.;Neema, K. V.. And the article was included in Indian Journal of Heterocyclic Chemistry in 2013.COA of Formula: C13H10OS This article mentions the following:
Chalcones were prepared by reacting 2-acetylthiophene and aromatic aldehydes in presence of NaOH in alc. medium. The resultant chalcones underwent selective cyclization with Ph hydrazine to yield the title compounds pyrazoline derivatives The structures of the synthesized compounds were confirmed by IR, 1H NMR, Mass spectra and elemental anal. These compounds were screened for their antimicrobial and antifungal activity. Some of the final synthesized compounds have exhibited promising antibacterial activity against Gram neg. bacteria and promising antifungal activity against A. flavus. In the experiment, the researchers used many compounds, for example, 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0COA of Formula: C13H10OS).
3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.COA of Formula: C13H10OS
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem