Determination of nine nonionic fluorescent whitening agent residues in polyester fiber textile by HPLC/FLD was written by Wu, Xiao-qiong;Ding, You-chao;Tang, Juan;Xu, Hai;Zheng, Dan-dan. And the article was included in Yinran Zhuji in 2016.Safety of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene This article mentions the following:
A sample pertreatment coupled to high performance with fluorescent detector (HPLC/FLD) method was developed for determination of nine nonionic fluorescent whitening agents, including 1,2-bis(5-methyl-2-benzoxazole)ethylene (DT), 7-diethylamino-4-methylcoumarin (SWN), 2,2′-(2,5-thiophenediyl)bis[5-(1,1-dimethylethyl)-benzoxazole] (OB), 2-[4-[2-[4-(2-benzoxazolyl)phenyl]ethenyl]phenyl]-5-methyl-benzoxazole (KSN), 1,4-bis(2-cyanostyry)benzene (ER-I), 1-(2-cyanostyryl)-4-1-(2-cyanostyryl)-4-(4-cyanostyryl)benzene (ER-II), 2,2′-(1,4-naphthalenediyl)bis-benzoxazole (KCB), 4,4′-bis[2-(2-methoxyphenyl)ethenyl]-1′-biphenyl (OB-I), 2,2′-(1,2-ethenediyldi-4,1-phenylene)bis(5-methylbenzoxazole) (OB-II) in textile. The sample was extracted with xylene and concentrated, and then qual. and quant. analyzed by HPLC/FLD. The separation of target compounds was performed on a phenomenex Gemini 5u C18 (150 mm ×4.6 mm, 5 μm) column by gradient elution using acetonitrile/ammonium acetate solution (containing 2.5 mmol/L ammonium acetate) as mobile phase. The correlation coefficients of nine kinds of nonionic fluorescent whitening agents was not less than 0.9993. The limits of quantification of the nine compounds (LOQs, S/V=10) were 0.70∼0.95 mg/kg. The average recoveries of the nine compounds ranged from 83.0% to 100% with the relative standard deviations (RSDs) of 4.0% ∼8.8%. The method was simple and accurate, which had a certain practical valve. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5Safety of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene).
2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Safety of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem