Efficient one pot multi-component domino Aldol condensation-Michael addition-Suzuki coupling reaction for the highly functionalized quinolines was written by Ubba, Eethamukkala;Kumar, Y. Suneel;Dasaradhan, C.;Khan, Fazlur-Rahman Nawaz;Jeong, Euh Duck;Chung, Eun Hyuk. And the article was included in Tetrahedron Letters in 2015.Formula: C8H7BO2S This article mentions the following:
A parallel and advantageous multi-component one pot reaction has been developed utilizing domino Aldol condensation-Michael addition-Suzuki coupling approach for a variety of 2,3-disubstituted highly functionalized quinolines. The domino reactions of 2-chloro-3-formylquinolines, acetophenones, and distinctive boronic acids, were carried out utilizing PdCl2(PPh3)2/tripotassium phosphate/ethanol-water system. At 80 °C they gave diversified functionalized quinolines in good yields. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6Formula: C8H7BO2S).
Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Formula: C8H7BO2S
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem