Visible-Light-Induced [4+2] Annulation of Thiophenes and Alkynes to Construct Benzene Rings was written by Song, Chunlan;Dong, Xin;Wang, Zhongjie;Liu, Kun;Chiang, Chien-Wei;Lei, Aiwen. And the article was included in Angewandte Chemie, International Edition in 2019.Reference of 1795-01-3 This article mentions the following:
Herein, an efficient strategy was developed for visible-light induced photocatalyzed [4+2] annulation of thiophenes and alkynes to afford substituted aromatic compounds Valuable drugs and amino acids were also well tolerated. Moreover, DFT calculations explained the high regioselectivity of the reaction. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Reference of 1795-01-3).
3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Reference of 1795-01-3
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem