Design and facile synthesis of 6-(benzothiophen-3-yl)-3-para-substituted-[1,2,4] triazolo [3,4-a] phthalazine derivatives as anti-microbial agents was written by Prabhakar, V.;Sudhakar Babu, K.;Ravindranath, L. K.;Lakshmi Reddy, I.;Latha, J.. And the article was included in Research Journal of Chemical Sciences in 2016.Computed Properties of C8H7BO2S This article mentions the following:
The synthesis, characterization and screening the biol. activity of the series of 6-(benzothiophen-3-yl)-3-para-substituted-[1,2,4]triazolo[3,4-a]phthalazines I [R = H, 4-Me, 2,5-di-F, etc.] with good yields were reported. The synthesized compounds I were characterized by IR, 1H-NMR, 13C-NMR and mass spectral data. The anti-microbial activity of the compounds I were screened by disk diffusion method. Compounds I [R = 4-F, 2,5-di-F, 4-F3C] demonstrated good antimicrobial activity against all the tested microbial strains. Compound I [R = 2,5-di-F] was showed good antibacterial and antifungal activities. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6Computed Properties of C8H7BO2S).
Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Computed Properties of C8H7BO2S
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem