Metal-Free Dehydrogenative Double C-H Sulfuration To Access Thieno[2,3-b]indoles Using Elemental Sulfur was written by Liu, Jianming;Zhang, Yanyan;Yue, Yuanyuan;Wang, Zhixian;Shao, Huibin;Zhuo, Kelei;Lv, Qingzhang;Zhang, Zhiguo. And the article was included in Journal of Organic Chemistry in 2019.Recommanded Product: 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one This article mentions the following:
A base-promoted metal-free approach for the synthesis of thieno[2,3-b]indole derivatives is reported. This method combined four C-H σ-bond cleavage reactions of two different kinds of C-H bonds and two C-S σ-bond formation processes. A series of thieno[2,3-b]indoles were obtained starting from 3-benzylindole derivatives with good yields and high regioselectivity, with the elemental sulfur serving as a cheap and readily available sulfur source. Good efficiency could be maintained even when the reaction was performed on a gram scale. A plausible mechanism was proposed on the basis of mechanistic studies. In the experiment, the researchers used many compounds, for example, 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0Recommanded Product: 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one).
3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is also used in the manufacturing of dyes such as thioindigo.Recommanded Product: 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem