Raney nickel desulfurization was written by Hurd, Charles D.;Rudner, Bernard. And the article was included in Journal of the American Chemical Society in 1951.Formula: C7H9NO3S This article mentions the following:
Three Raney-Ni preparations were investigated in the desulfuration of S-containing compounds o-Tolyl isothiocyanate or o-tolylthiourea gave o-MeC6H4NH2; PhSO2 derivative, white plates from 80% EtOH, m. 125-6° and 124-4.5°; Bz derivative, m. 144-5° and 142-3°. There were no secondary amines. Thiobenzanilide gave PhNHCH2Ph; PhCONHPh, m. 164-6°; benzenesulfon(N-benzylanilide), m. 117-18°; benzo(N-benzylanilide), m. 106.5-107° (white needles from EtOH). 2-Mercaptobenzothiazole gave mostly PhNH2, with smaller amounts of o-H2NC6H4SH and benzothiazole; picrate, needles from 90% EtOH, m. 178-9.5°. 2-Mercapto- (I) and 2-amino-4-phenylthiazole (II) yielded MeCOPh; 2,4-dinitrophenylhydrazone, m. 246-8°. I also gave 4-phenylthiazole; HCl salt, m. 76-8°; picrate, m. 162-3°. II gave MeNH2 and PhEtNH. 2-Amino- and 2-mercapto-4-hydroxythiazole gave AcNH2 and AcH, resp. 2-Thienyl Me ketone gave BuCOMe [2,4-dinitrophenylhydrazone, m. 104-5° (orange-red rods from EtOH)], and small amounts of AcH and EtOH. In the experiment, the researchers used many compounds, for example, 2-Amino-3-hydroxy-3-(thiophen-2-yl)propanoic acid (cas: 32595-59-8Formula: C7H9NO3S).
2-Amino-3-hydroxy-3-(thiophen-2-yl)propanoic acid (cas: 32595-59-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Formula: C7H9NO3S
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem