Copper-Catalyzed Cross-Coupling of Arylacetylenes with Bromodifluoroacetamides was written by Hu, Guo-Qin;Yao, Li-Wei;Gui, Shu-Sheng;Geng, Chuang;Zhang, Wen-Yan;Liu, Jing-Hui;Zhao, Bin. And the article was included in Synlett in 2022.SDS of cas: 4298-52-6 This article mentions the following:
A copper-catalyzed radical difluoroalkylation of arylacetylenes with bromodifluoroamides has been developed. The reaction exhibits good functional group tolerance and allows access to a variety of substituted α-alkynyl-α,α-difluoroacetamides in moderate to good yields. The potential for scale-up reaction and products derivatization also makes this method attractive for practical applications. Preliminary mechanistic studies suggest that a radical reaction pathway might be involved in the catalytic system. In the experiment, the researchers used many compounds, for example, 2-Ethynylthiophene (cas: 4298-52-6SDS of cas: 4298-52-6).
2-Ethynylthiophene (cas: 4298-52-6) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.SDS of cas: 4298-52-6
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem