Regioselective Dichotomy in Ru(II)-Catalyzed C-H Annulation of Aryl Pyrazolidinones with 1,3-Diynes was written by Sontakke, Geetanjali S.;Ghosh, Chiranjit;Pal, Kuntal;Volla, Chandra M. R.. And the article was included in Journal of Organic Chemistry in 2022.SDS of cas: 67237-53-0 This article mentions the following:
Herein, authors present a substrate-controlled regiodivergent strategy for the selective synthesis of C3 or C2-alkynylated indoles via ruthenium-catalyzed [3 + 2]-annulation of readily available pyrazolidinones and 1,3-diynes. Remarkably, C3-alkynylated indoles were obtained in good yields when 1,4-diarylbuta-1,3-diynes were employed as the coupling partners. On the other hand, dialkyl-1,3-diynes led to the selective formation of C2-alkynylated indoles. The key features of the strategy are the operationally simple conditions and external-oxidant-free, broad-scope, and substrate-switchable indole synthesis. Scale-up reactions and further transformations expanded the synthetic utility of the protocol. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0SDS of cas: 67237-53-0).
3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.SDS of cas: 67237-53-0
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem