Surface modification by polyzwitterions of the sulfabetaine-type, and their resistance to biofouling was written by Schoenemann, Eric;Laschewsky, Andre;Wischerhoff, Erik;Koc, Julian;Rosenhahn, Axel. And the article was included in Polymers (Basel, Switzerland) in 2019.Reference of 1072-53-3 This article mentions the following:
Films of zwitterionic polymers are increasingly explored for conferring fouling resistance to materials. Yet, the structural diversity of polyzwitterions is rather limited so far, and clear structure-property relationships are missing. Therefore, we synthesized a series of new polyzwitterions combining ammonium and sulfate groups in their betaine moieties, so-called poly(sulfabetaine)s. Their chem. structures were varied systematically, the monomers carrying methacrylate, methacrylamide, or styrene moieties as polymerizable groups. High molar mass homopolymers were obtained by free radical polymerization Although their solubilities in most solvents were very low, brine and lower fluorinated alcs. were effective solvents in most cases. A set of sulfabetaine copolymers containing about 1 mol % (based on the repeat units) of reactive benzophenone methacrylate was prepared, spin-coated onto solid substrates, and photo-cured. The resistance of these films against the nonspecific adsorption by two model proteins (bovine serum albumin-BSA, fibrinogen) was explored, and directly compared with a set of references The various polyzwitterions reduced protein adsorption strongly compared to films of poly(nbutyl methacrylate) that were used as a neg. control. The poly(sulfabetaine)s showed generally even somewhat higher anti-fouling activity than their poly(sulfobetaine) analogs, though detailed efficacies depended on the individual polymer-protein pairs. Best samples approach the excellent performance of a poly(oligo(ethylene oxide) methacrylate) reference In the experiment, the researchers used many compounds, for example, 1,3,2-Dioxathiolane 2,2-dioxide (cas: 1072-53-3Reference of 1072-53-3).
1,3,2-Dioxathiolane 2,2-dioxide (cas: 1072-53-3) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is also used in the manufacturing of dyes such as thioindigo.Reference of 1072-53-3
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem