Evaluation of Nutritional Substances and Investigation of Antioxidant and Antimicrobial Potentials of Boerhavia diffusa with in Silico Molecular Docking was written by Kaviya, Mohandass;Balasubramanian, Balamuralikrishnan;Bharathi, Kathirvel;Malaisamy, Arunkumar;Al-Dhabi, Naif Abdullah;Mariadhas, Valan Arasu;Anand, Arumugam Vijaya;Liu, Wenchao. And the article was included in Molecules in 2022.Recommanded Product: 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene This article mentions the following:
Boerhavia diffusa L. Nyctanginaceae (B.diffusa) is a medicinal herb commonly considered as a weed. The exploration of phytochems. in different parts of B.diffusa with different solvents will create awareness, along with the suitable solvent and method for extraction of pharmaceutical compounds Hence, the present study focuses on phytochem. anal. of B.diffusa leaves, stems, and roots in various solvents with hot and cold extraction The decoctions performed well in most of the qual. and quant. tests, along with the DPPH assay. The aqueous extract showed a good result in the FRAP assay and ABTS assay. In the antimicrobial test, the B.diffusa root ethanol extract inhibited the growth of Pseudomonas aeruginosa and Staphylococcus aureus with zones of inhibition of about 8 mm and 20 mm at 200 g concentration, resp. Using a mol. docking approach, the top four ranked mols. from the crude extract of B.diffusa profiled from GC-MS spectroscopy in terms of growth inhibition of the pathogenic bacterium P.aeruginosa were selected; among them, 2-(1,2 dihydroxyethyl)-5-[[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl]oxy]oxolane-3,4-diol exhibited the min. binding score, revealing high affinity in complex. B.diffusa is highly nutritious, and the maceration and decoction extracts were similar except for the chloroform extract that was found to be weak. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5Recommanded Product: 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene).
2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Recommanded Product: 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem