Synthesis of Cyclopentene Derivatives via Electrochemically Induced Intermolecular Selective (3+2) Annulation was written by Guan, Zhipeng;Zhu, Shuxiang;Ye, Yayu;Li, Xiangwei;Liu, Yanlong;Wang, Pengjie;Zhang, Heng;Huang, Zhiliang;Lei, Aiwen. And the article was included in Angewandte Chemie, International Edition in 2022.Product Details of 4298-52-6 This article mentions the following:
An electrochem. mediator-induced intermol. selective (3+2) annulation of readily available alkenes and alkynes/alkenes, which provided a simple and efficient method for the synthesis of a library of decorated cyclopentenes and cyclopentanes was developed. This protocol features high efficiency, mild reaction conditions, broad substrate scope, good functional group tolerance and high regioselectivity. Potential applications was demonstrated by gram-scale synthesis as well as the construction of structural diversity and complexity. A preliminary mechanistic investigation was performed, which indicated that an iodine radical and carbon radicals are involved in this transformation. In the experiment, the researchers used many compounds, for example, 2-Ethynylthiophene (cas: 4298-52-6Product Details of 4298-52-6).
2-Ethynylthiophene (cas: 4298-52-6) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Product Details of 4298-52-6
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem