Enantioselective Trost alkynylation with 2E,4E-5-bromo-2,4-pentadienal was written by Ervik, Karina;Vidar Hansen, Trond. And the article was included in Tetrahedron Letters in 2022.SDS of cas: 67237-53-0 This article mentions the following:
The synthetically useful aldehyde 2E,4E-5-bromo-2,4-pentadienal were subjected to the enantioselective Trost alkynylation protocol, yielding highly functionalized propargylic secondary alcs. in an enantioselective manner. In most cases, the isolated yields and enantiomeric excess of the products were modest to high, but several products were formed in both high yields and enantiomeric excess. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0SDS of cas: 67237-53-0).
3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.SDS of cas: 67237-53-0
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem