Catalytic activity and mechanistic investigation of 1D 2-picolinic acid based Cu(II) coordination polymer in the selective construction of 1,4-disubstituted triazoles was written by Aier, Merangmenla;Gayen, Firdaus Rahaman;Puzari, Amrit. And the article was included in Scientific Reports in 2022.COA of Formula: C6H4S This article mentions the following:
The catalytic activity of 1D 2-picolinic acid based Cu(II) coordination polymer (CP1) in click reaction to selectively generate 1,4-disubstituted 1,2,3-triazoles has been evaluated. The CP1 catalyst loading of 2 mol% was applied successfully in the reactions of primary azides with diverse terminal alkynes in green solvent (aqueous ethylene glycol). Moreover, the one-pot, multicomponent click reaction involving benzyl bromide, sodium azide, and phenylacetylene was also catalyzed by CP1. The findings show that 2-picolinic acid based Cu(II) coordination polymer catalytic systems are highly efficient for green click triazoles synthesis. DFT calculation supported the plausible mechanism involved in the CP1 catalyzed click reaction. In the experiment, the researchers used many compounds, for example, 2-Ethynylthiophene (cas: 4298-52-6COA of Formula: C6H4S).
2-Ethynylthiophene (cas: 4298-52-6) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.COA of Formula: C6H4S
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem